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Showing posts from January, 2021

Early warning signals could help monitor disease outbreaks

New research suggests early warning signals (EWSs) could help in the monitoring of disease outbreaks, such as COVID-19. The study found warnings could be detected weeks earlier than any rapid increase in cases. The findings could help governments and policy makers improve the accuracy of their decisions and allow timely interventions if needed. from Top Health News -- ScienceDaily https://ift.tt/3DvxDk4 via IFTTT

Scientists solve long-standing mystery by a whisker

Neuroscientists have experimented on mice to identify the brain region that functions beyond sensory encoding and motor encoding, potentially opening up new directions to studying the cellular and circuit mechanisms of sensory-motor transformations. The researchers report a cortical region traditionally defined as whisker motor cortex in mice is most directly related to the transformation process. from Top Health News -- ScienceDaily https://ift.tt/2YuaXyn via IFTTT

What we see shapes what we hear

People often move their hands up and down to 'highlight' what they are saying. Are such 'beat gestures' important for communication? Researchers created words with an ambiguous stress pattern and asked listeners what they heard (DIScount or disCOUNT?). The beat gestures people saw influenced what they heard, showing that listeners quickly integrate verbal and visual information during speech recognition. from Top Health News -- ScienceDaily https://ift.tt/3r4PmJl via IFTTT

Genetic analysis of symptoms yields new insights into PTSD

A new study uncovers intriguing genetic similarities between PTSD and other mental health disorders such as anxiety, bipolar disorder, and schizophrenia. The findings also suggest that existing drugs commonly used for other disorders might be modified to help treat individual symptoms of multiple disorders. from Top Health News -- ScienceDaily https://ift.tt/3tdHIOz via IFTTT

Frequent cannabis use by young people linked to decline in IQ

A study has found that adolescents who frequently use cannabis may experience a decline in Intelligence Quotient (IQ) over time. The findings of the research provide further insight into the harmful neurological and cognitive effects of frequent cannabis use on young people. from Top Health News -- ScienceDaily https://ift.tt/3cqRw1R via IFTTT

Using zirconium as an additive in super-strong composite materials

Ceramic matrix composites (CMCs) are incredibly strong materials used in jet engines, gas turbines, and cutting tools for nickel superalloys. Aluminum oxide (Al2O3) is hard and chemically inert, and tungsten carbide (WC) is used as a superhard material, but past efforts to create an Al2O3-WC CMC yielded unsatisfactory results. Recently, a study by Japanese scientists shows that adding zirconium atoms results in improved Al2O3-WC CMCs. from Top Health News -- ScienceDaily https://ift.tt/3r6yhyt via IFTTT

Scientists discover a new pathway essential for blood formation

Scientists have discovered how a protein called Tip60 plays a vital role in the renewal of blood cells in the body. Without it, the stem cells that make new blood suffer catastrophic damage. This discovery could lead to better treatments for life-threatening blood-related diseases like leukemia. from Top Health News -- ScienceDaily https://ift.tt/2MH7lqo via IFTTT

How the brain is programmed for computer programming?

Expert computer programmers show higher proficiency in certain behavioral and attention skills than their novice peers. To identify the responsible brain regions, scientists used fMRI to analyze the brain activities of 30 programmers of different skill level, finding that seven regions of the frontal, parietal and temporal cortices in expert programmers' brains are fine-tuned for programming. The findings could provide better methods and tools for everyone to learn programming. from Top Health News -- ScienceDaily https://ift.tt/3r4lBZ9 via IFTTT

Gendered division of labor shaped human spatial behavior

Research based on the daily movements of people living in a contemporary hunter-gatherer society provides new evidence for links between the gendered division of labor in human societies over the past 2.5 million years and differences in the way men and women think about space. from Top Health News -- ScienceDaily https://ift.tt/3r5gqIk via IFTTT

Hypnotic suggestions can make a complex task easy by helping vision fill in the blanks

New research demonstrates that hypnosis -- the process of focusing a person's attention on a specific task or sensation -- can turn a normally difficult visual task into a far easier one by helping individuals mentally 'fill in the gaps' of missing visual cues. from Top Health News -- ScienceDaily https://ift.tt/36pWbNt via IFTTT

Technology could upend DNA sequencing for diagnosing certain DNA mutations

Doctors are increasingly using genetic signatures to diagnose diseases and determine the best course of care, but using DNA sequencing and other techniques to detect genomic rearrangements remains costly or limited in capabilities. However, an innovative breakthrough promises to diagnose DNA rearrangement mutations at a fraction of the cost with improved accuracy. from Top Health News -- ScienceDaily https://ift.tt/3csuWFW via IFTTT

Pain patients who take opioids can't get in the door at over half of primary care clinics

People who take opioid medications for chronic pain may have a hard time finding a new primary care clinic that will take them as a patient if they need one, according to a new 'secret shopper' study of hundreds of clinics across the country. Stigma against long-term users of prescription opioids, likely related to the prospect of taking on a patient who might have an opioid use disorder or addiction, appears to play a role. from Top Health News -- ScienceDaily https://ift.tt/3r0SeXq via IFTTT

A NEAT reduction of complex neuronal models accelerates brain research

Unlike their simple counterparts in artificial intelligence (AI) applications, neurons in the brain use dendrites - their intricate tree-like branches - to find relevant chunks of information. Now, neuroscientists have discovered a new computational method to make complex dendrite models much simpler. These faithful reductions may lead AI applications to process information much like the brain does. from Top Health News -- ScienceDaily https://ift.tt/3r7TyYz via IFTTT

'Achilles' heel' of cancer cells revealed

A new study shows, for the first time, how an abnormal number of chromosomes (aneuploidy) -- a unique characteristic of cancer cells that researchers have known about for decades -- could become a weak point for these cells. The study could lead to the development of future drugs that will use this vulnerability to eliminate the cancer cells. from Top Health News -- ScienceDaily https://ift.tt/3tc8wiq via IFTTT

Blood pressure can be controlled without drugs after spinal cord injury

Researchers have created the first platform to understand the mechanisms underlying blood pressure instability after spinal cord injury. The discovery has led to a new cutting-edge solution. Spinal cord stimulators can bridge the body's autonomous regulation system, controlling blood pressure without medication. from Top Health News -- ScienceDaily https://ift.tt/3pAjw6P via IFTTT

Scientists jump-start two people's brains after coma

In 2016, a team reported that a 25-year-old man recovering from a coma had made remarkable progress following a treatment to jump-start his brain using ultrasound. Now, researchers report that two more patients with severe brain injuries have also made impressive progress thanks to the same technique. from Top Health News -- ScienceDaily https://ift.tt/2KZWs2f via IFTTT

Scientists discover a new promising target for diabetes treatment

Researchers have discovered a novel and druggable insulin inhibitory receptor, named inceptor. The blocking of inceptor function leads to an increased sensitisation of the insulin signaling pathway in pancreatic beta cells. This might allow protection and regeneration of beta cells for diabetes remission. from Top Health News -- ScienceDaily https://ift.tt/39uFYbP via IFTTT

New catalyst moves seawater desalination, hydrogen production closer to commercialization

Seawater is abundant and cheap, making it a tempting resource to meet the world's growing need for clean drinking water and carbon-free energy. Now researchers have reported a new catalyst that can be made quickly and inexpensively, bringing the technology closer to commercial reality. from Top Health News -- ScienceDaily https://ift.tt/2MwTxib via IFTTT

Putting bugs on the menu, safely

The thought of eating insects is stomach turning for many, but new research is shedding light on allergy causing proteins which could pose serious health risks for those suffering from shellfish allergy. The research identified 20 proteins found in cricket food products which could cause serious allergic reactions. from Top Health News -- ScienceDaily https://ift.tt/3osq2uY via IFTTT

Malaria threw human evolution into overdrive on this African archipelago

Malaria is an ancient scourge, but it's still leaving its mark on the human genome. And now, researchers have uncovered recent traces of adaptation to malaria in the islanders of Cabo Verde -- thanks to a genetic mutation, inherited from their African ancestors, that prevents a type of malaria parasite from invading red blood cells. The findings represent one of the speediest, most dramatic changes measured in the human genome. from Top Health News -- ScienceDaily https://ift.tt/3abxtBQ via IFTTT

Scientists find key function of molecule in cells crucial for regulating immunity

Scientists discovered that AIM2 is important for the proper function of regulatory T cells, or Treg cells, and plays a key role in mitigating autoimmune disease. Treg cells are a seminal population of adaptive immune cells that prevents an overzealous immune response, such as those that occurs in autoimmune diseases. from Top Health News -- ScienceDaily https://ift.tt/2Yl93Aa via IFTTT

Healthy lifespan analysis using nematodes

Researchers have developed an automated measurement system to assess healthy lifespan using nematodes. This system performs a mini-population analysis to classify specific populations of nematodes based on qualitative differences in lifespan. Since there are many similarities between the mechanisms that determine the lifespan of nematodes and humans, this system could make it easier to develop drugs and find foods that extend the healthy lifespan of humans. from Top Health News -- ScienceDaily https://ift.tt/39pTT2N via IFTTT

Detecting trace amounts of multiple classes of antibiotics in foods

Widespread use of antibiotics in human healthcare and livestock husbandry has led to trace amounts of the drugs ending up in food products. Long-term consumption could cause health problems, but it's been difficult to analyze more than a few antibiotics at a time because they have different chemical properties. Now, researchers have developed a method to simultaneously measure 77 antibiotics in a variety of foods. from Top Health News -- ScienceDaily https://ift.tt/2Ypviow via IFTTT

Researchers develop technique to replicate bone-remodeling processes

A multidisciplinary research team has developed a technique to replicate bone tissue complexity and bone-remodeling processes. This breakthrough could help researchers further their study of bone biology and assist in improving development of drugs for osteoporosis. from Top Health News -- ScienceDaily https://ift.tt/3iVpAEo via IFTTT

T cells can mount attacks against many SARS-CoV-2 targets -- even on new virus variant

A new study suggests that T cells try to fight SARS-CoV-2 by targeting a broad range of sites on the virus -- beyond the key sites on the virus's spike protein. By attacking the virus from many angles, the body has the tools to potentially recognize different SARS-CoV-2 variants. from Top Health News -- ScienceDaily https://ift.tt/3t2s7Bf via IFTTT

AI used to predict early symptoms of schizophrenia in relatives of patients

Researchers have taken a step forward in developing an artificial intelligence tool to predict schizophrenia by analyzing brain scans. The tool was used to analyze functional magnetic resonance images of 57 healthy first-degree relatives (siblings or children) of schizophrenia patients. It accurately identified the 14 individuals who scored highest on a self-reported schizotypal personality trait scale. from Top Health News -- ScienceDaily https://ift.tt/3iRz9US via IFTTT

Malaria tricks the brain's defense system

Malaria is one of the most common causes of death in children in Africa. When the parasite builds up in the blood vessels of the brain, it develops into one of the most dangerous forms of the disease, cerebral malaria. Though it wasn't certain if the parasite was able to penetrate the brain tissue, now researchers have found parasites can do that and have mapped the mechanism they utilize. from Top Health News -- ScienceDaily https://ift.tt/3ppnz5L via IFTTT

Ancient proteins help track early milk drinking in Africa

Got milk? The 1990s ad campaign highlighted the importance of milk for health and wellbeing, but when did we start drinking the milk of other animals? And how did the practice spread? A new study led by scientists from Germany and Kenya highlights the critical role of Africa in the story of dairying, showing that communities there were drinking milk by at least 6,000 years ago. from Top Health News -- ScienceDaily https://ift.tt/2M2wAUc via IFTTT

Epilepsy research focused on astrocytes

A significant number of epilepsy patients does not respond to currently available drugs. Researchers now addressed a cell type in the brain that has so far not received much attention in epilepsy therapy. They describe how astrocytes might be a potential new target to better treat this disease. from Top Health News -- ScienceDaily https://ift.tt/36kUMb7 via IFTTT

Missing protein helps small cell lung cancer evade immune defenses

Small cell lung cancer (SCLC) cells are missing a surface protein that triggers an immune response, allowing them to hide from one of the body's key cancer defenses, a new study suggests. The findings could lead to new treatments for SCLC, which has no effective therapies. from Top Health News -- ScienceDaily https://ift.tt/3pChPGd via IFTTT

Light pollution linked to preterm birth increase

Scientists conducted the first study to examine the fetal health impact of light pollution based on a direct measure of skyglow, an important aspect of light pollution. Using an empirical regularity discovered in physics, called Walker's Law, a team found evidence of reduced birth weight, shortened gestational length and preterm births. from Top Health News -- ScienceDaily https://ift.tt/2MvNCtG via IFTTT

Highly specific synaptic plasticity in addiction

Addiction, or substance use disorder (SUD), is a complex neurological condition that includes drug-seeking behavior among other cognitive, emotional and behavioral features. Synaptic plasticity, or changes in the way neurons communicate with one another, drives these addictive behaviors. A new study now shows that players in the extracellular environment - not just at neuronal interfaces - contribute to addiction plasticity. from Top Health News -- ScienceDaily https://ift.tt/39k0gEV via IFTTT

A compound that slows bone loss, and a resource for developing treatments to slow aging

A compound that extends lifespan in a tiny nematode worm slows bone loss in aging mice. That surprising result comes from a longitudinal and functional study of 700 aging mice, a project that provides a treasure trove of data for researchers aiming to develop therapeutics to slow aging and age-related diseases. from Top Health News -- ScienceDaily https://ift.tt/3afdpyy via IFTTT

Genome-editing tool TALEN outperforms CRISPR-Cas9 in tightly packed DNA

Researchers used single-molecule imaging to compare the genome-editing tools CRISPR-Cas9 and TALEN. Their experiments revealed that TALEN is up to five times more efficient than CRISPR-Cas9 in parts of the genome, called heterochromatin, that are densely packed. Fragile X syndrome, sickle cell anemia, beta-thalassemia and other diseases are the result of genetic defects in the heterochromatin. from Top Health News -- ScienceDaily https://ift.tt/3iSqRfw via IFTTT

Pace of prehistoric human innovation could be revealed by 'linguistic thermometer'

A physics professor has joined forces with language experts to build a 'linguistic thermometer' that can record the temperature of 'hot' or 'cold' (ie fast or slow) developments in modern linguistic features to create a computer-based model that can provide a better understanding of the development in human language and innovation stretching back to pre-history. from Top Health News -- ScienceDaily https://ift.tt/2MbvqWn via IFTTT

New control mechanism in innate immune system

Although the protein ITIH4 is found in large amounts in the blood, its function has so far been unknown. By combining many different techniques, researchers have discovered that ITIH4 inhibits proteases in the innate immune system via an unknown mechanism. from Top Health News -- ScienceDaily https://ift.tt/3qOu96a via IFTTT

A benchmark for single-electron circuits

Manipulating individual electrons with the goal of employing quantum effects offers new possibilities in electronics. In order to gain new insights into the physical origin and into metrological aspects of the small, but inevitable fundamental uncertainties governed by the rules of quantum mechanics, scientists have collaborated to develop a statistical testing methodology. from Top Health News -- ScienceDaily https://ift.tt/2MaT5pI via IFTTT

Biologists unravel full sequence of DNA repair mechanism

Researchers have observed the entire sequence in break-induced replication, a method by which organisms from viruses to humans repair breaks in DNA that cannot be fixed otherwise but can introduce or cause genomic rearrangements and mutations contributing to cancer development. from Top Health News -- ScienceDaily https://ift.tt/3opgEIu via IFTTT

Dietary adherence and the fight against obesity

While eating less and moving more are the basics of weight control and obesity treatment, finding ways to help people adhere to a weight-loss regimen is more complicated. Understanding what features make a diet easier or more challenging to follow can help optimize and tailor dietary approaches for obesity treatment. from Top Health News -- ScienceDaily https://ift.tt/2YkUexm via IFTTT

Protein anchors as a newly discovered key molecule in cancer spread and epilepsy

Certain anchor proteins inhibit a key metabolic driver that plays an important role in cancer and developmental brain disorders. Scientists discovered this molecular mechanism, which could open up new opportunities for personalized therapies for cancer and neuronal diseases. from Top Health News -- ScienceDaily https://ift.tt/3sWntou via IFTTT

Gut microbiota reveals whether drug therapies work in inflammatory bowel diseases

A study indicates that the gut microbiota of patients suffering from inflammatory gastrointestinal disorders can be used to predict whether they will benefit from expensive therapies. The study also confirms the key role of therapies that have a beneficial effect on the gut microbiota in inflammatory bowel diseases. from Top Health News -- ScienceDaily https://ift.tt/2YjQ5K4 via IFTTT

Competition among human females likely contributed to concealed ovulation

Humans are among the few species that lack overt physical indicators of female fertility. One explanation for concealed ovulation in human females is that hiding fertility from males helps females secure resources from males for raising children. A new model developed by a team of evolutionary scientists casts doubt on this idea, showing that females might have evolved to conceal ovulation from one another, not from males. from Top Health News -- ScienceDaily https://ift.tt/3qQO18M via IFTTT

No overall difference in concussion recovery time for male and female college athletes

Researchers found female and male collegiate athletes take approximately the same amount of time to recover from a concussion, with subtle differences in recovery time depending on the type of sports being played and the division level of the sport. The findings suggest that equity in access to sports medical care among college athletes may be contributing to these similar outcomes. from Top Health News -- ScienceDaily https://ift.tt/3cbBE2W via IFTTT

Rich European countries have higher atrial fibrillation death rates than least wealthy

The wealthiest countries in Europe have higher death rates from atrial fibrillation than the least wealthy and these death rates are increasing more rapidly than incidence rates, according to the first analysis of its kind. The study also found that women who developed the condition were more likely than men to die from it in all 20 European countries studied. from Top Health News -- ScienceDaily https://ift.tt/3pnbApp via IFTTT

Fine tuning first-responder immune cells may reduce TBI damage

Immediately after a traumatic brain injury and as long as one year later, there are increased levels of immune cells called ILCs in the brain promoting inflammation, which can worsen brain damage, scientists report. They also report for the first time that the cell energy sensor AMPK is a brake that can stop what becomes a chronic state of destructive inflammation driven by these ILCs, or innate lymphoid cells. from Top Health News -- ScienceDaily https://ift.tt/3a1OkH2 via IFTTT

Domino effects and synchrony in seizure initiation

In a brain with a neurological disorder like epilepsy, synchronization between groups of neurons can grow to a dangerous extent when a collection of brain cells begins to emit excess electricity. Researchers used a mathematical model to explore the interplay between neurons that leads to these transitions in synchronization during the onset of seizures. from Top Health News -- ScienceDaily https://ift.tt/2M5hjld via IFTTT

Newly discovered subset of brain cells fight inflammation with instructions from the gut

Astrocytes are the most abundant type of cells within the central nervous system (CNS), but they remain poorly characterized. Researchers have long assumed that astrocytes' primary function is to provide nutrients and support for the brain's more closely scrutinized nerve cells; over the years, however, increasing evidence has shown that astrocytes can also actively promote neurodegeneration, inflammation, and neurological diseases. from Top Health News -- ScienceDaily https://ift.tt/3qP6vGM via IFTTT

Promising way to find new cancer drugs

The enzymes in human cells known as histone deacetylases, or HDACs, are targets for a handful of anticancer drugs because of their ability to affect gene expression. Now, researchers have developed a new method to investigate how these enzymes work on a molecular level. This new method can also help identify more precise possible anti-cancer drug candidates at a very high pace. from Top Health News -- ScienceDaily https://ift.tt/2M1SSFi via IFTTT

Immune cells found in the brain are behind the depression experienced in inflammation

Special immune cells found in the brain, microglia, play a key role in the processes that make you feel uneasy and depressed in correlation with inflammation. This is the conclusion of a study using mice. The results suggest that microglial cells contribute to the negative mood experienced during several neurological diseases, and maybe also depression. from Top Health News -- ScienceDaily https://ift.tt/3a4CH23 via IFTTT

Watching decision making in the brain

Neuroscientists and engineers have developed a system that can show the neural process of decision making in real time, including the mental process of flipping between options before expressing a final choice. from Top Health News -- ScienceDaily https://ift.tt/3qWynsF via IFTTT

Continuous monitoring of proteins a game-changer for patients with deteriorating health

A world-first discovery could become a game-changer for patients at risk of rapid health deterioration, such as heart complications, stroke, sepsis and cancer. Researchers developed an antibody as a biosensor, to continuously monitor rapid changes in the concentration of EGFR, a protein present on cancer cells and in body fluids. from Top Health News -- ScienceDaily https://ift.tt/3qOCpDh via IFTTT

Women influenced coevolution of dogs and humans

A cross-cultural analysis found several factors may have played a role in building the relationship between humans and dogs, including temperature, hunting and surprisingly - gender. The analysis used ethnographic information from 144 traditional, subsistence-level societies from all over the globe. People were more likely to regard dogs as a type of person if the dogs had a special relationship with women -- such as having names and being treated as family. from Top Health News -- ScienceDaily https://ift.tt/3sQnRFb via IFTTT

No more needles for diagnostic tests?

Medical researchers have developed a biosensing microneedle patch that can be applied to the skin, capture a biomarker of interest and, thanks to its unprecedented sensitivity, allow clinicians to detect its presence. from Top Health News -- ScienceDaily https://ift.tt/3iI6qSh via IFTTT

Regulating the ribosomal RNA production line

The enzyme that makes RNA from a DNA template is altered to slow the production of ribosomal RNA (rRNA), the most abundant type of RNA within cells, when resources are scarce and the bacteria Escherichia coli needs to slow its growth. from Top Health News -- ScienceDaily https://ift.tt/3ohOtv0 via IFTTT

Possible new combo therapy for head and neck cancer

Researchers have tested a new combination therapy in animal models to see if they could find a way to make an already effective treatment even better. Since they're using a Food and Drug Administration-approved drug to do it, this could help people sooner than later. from Top Health News -- ScienceDaily https://ift.tt/2YbKWDW via IFTTT

Exercising muscle combats chronic inflammation on its own

Biomedical engineers have demonstrated that human muscle has an innate ability to ward off damaging effects of chronic inflammation when exercised. The discovery was made possible through the use of lab-grown, engineered human muscle, demonstrating the potential power of the first-of-its-kind platform in such research endeavors. from Top Health News -- ScienceDaily https://ift.tt/3iHhfUN via IFTTT

Geographic factors that affect HPV vaccination rates

A team of researchers have conducted the first-ever systematic review of area-level data reported in the United States between 2006 and 2020 to determine how geography, neighborhoods and sociodemographic factors impact HPV vaccination rates among adolescents and young adults. from Top Health News -- ScienceDaily https://ift.tt/3iTHzLH via IFTTT

New maintenance treatment for acute myeloid leukemia prolongs the lives of patients

Patients with acute myeloid leukemia (AML), the most common form of acute leukemia in adults, that has gone into remission following initial chemotherapy remain in remission longer and have improved overall survival when they are given a pill form of the cancer drug azacitidine as a maintenance treatment, according to a randomized, international phase 3 clinical trial. from Top Health News -- ScienceDaily https://ift.tt/3iMlWN1 via IFTTT

Depression in new fathers connected to relationship insecurities

Becoming a parent often brings great joy, but not always. Parenthood also entails challenges, stress and, for some people, it can trigger depression. A new study shows that male postnatal depression is more common in men who are insecure in their relationship with their partner. from Top Health News -- ScienceDaily https://ift.tt/366NwPS via IFTTT

Developmental origins of eczema and psoriasis discovered

Scientists have created a highly detailed map of skin, which reveals that cellular processes from development are re-activated in cells from patients with eczema and psoriasis inflammatory skin diseases. The study offers potential new drug targets for treating these painful skin diseases and provides a new understanding of inflammatory disease. The research could also provide a template for regenerating healthy skin in the laboratory. from Top Health News -- ScienceDaily https://ift.tt/2Y7UcsO via IFTTT

Combining best of both worlds for cancer modeling

Treatment options for many types of cancers remain limited, due partly to the in vitro tools used to model cancers and that results from animal studies do not always translate well to human disease. These shortcomings point to a clear need for a better, patient-specific model. Researchers suggest bioengineered microscale organotypic models can address this need. from Top Health News -- ScienceDaily https://ift.tt/2Mmo81x via IFTTT

On the trail of active ingredients from marine yeasts

Numerous natural products are awaiting discovery in all kinds of natural habitats. Especially microorganisms such as bacteria or fungi are able to produce diverse natural products with high biomedical application potential in particular as antibiotics and anticancer agents. Researchers have isolated red yeast of the species Rhodotorula mucilaginosa from a deep-sea sediment sample and analyzed for its genome and chemical constituents. The scientists succeeded in demonstrating its anticancer and antibacterial effects. from Top Health News -- ScienceDaily https://ift.tt/3a1S2QS via IFTTT

PTSD link to pandemic fears

A new study of 1040 online participants from five western countries explores people's response to the stresses of the escalating pandemic, finding more than 13 percent of the sample had post-traumatic stress disorder (PTSD) related symptoms consistent with levels necessary to qualify for a clinical diagnosis. from Top Health News -- ScienceDaily https://ift.tt/2LMneMb via IFTTT

Treating moms with postpartum depression helps their babies' brains

For the study 40 infants of women diagnosed with postpartum depression were matched with 40 infants of non-depressed mothers on infant age, gender and socioeconomic status. The mothers with postpartum depression received nine weeks of group CBT. The infants were all tested before the treatment and nine weeks later, including a questionnaire on the infant behaviour completed by the mother and her partner. from Top Health News -- ScienceDaily https://ift.tt/365n7C5 via IFTTT

Mitochondrial mutation increases the risk of diabetes in Japanese men

A new study of Type 2 diabetes (T2D) in Japanese populations has uncovered a previously uncharacterized genetic variant that puts male carriers at greater risk for the disease, as well as the mechanism by which it does so. The impact of the variant was most pronounced in sedentary men; those with the variant had a 65% greater rate of T2D than sedentary men without it. from Top Health News -- ScienceDaily https://ift.tt/39RX1DU via IFTTT

When a story is breaking, AI can help consumers identify fake news

Warnings about misinformation are now regularly posted on Twitter, Facebook, and other social media platforms, but not all of these cautions are created equal. New research from Rensselaer Polytechnic Institute shows that artificial intelligence can help form accurate news assessments -- but only when a news story is first emerging. from Top Health News -- ScienceDaily https://ift.tt/3bXqqPD via IFTTT

Detailed tumour profiling

As part of a clinical study, researchers are conducting a thorough and highly precise investigation into the molecular and functional properties of tumors. Their goal is to help physicians to better determine which treatment will best match every patient's cancer and thus be most effective. from Top Health News -- ScienceDaily https://ift.tt/364S9u1 via IFTTT

New, simplified genetic test effectively screens for hereditary cancers

Researchers have developed a new integrated genetic/epigenetic DNA-sequencing protocol known as MultiMMR that can identify the presence and cause of mismatch repair (MMR) deficiency in a single test from a small sample of DNA in colon, endometrial, and other cancers. This alternative to complex, multi-step testing workflows can also determine causes of MMR deficiency often missed by current clinical tests. from Top Health News -- ScienceDaily https://ift.tt/3iHnaZZ via IFTTT

Scientists make pivotal discovery on mechanism of Epstein-Barr virus latent infection

Researchers have discovered a new enzymatic function of the Epstein-Barr Virus (EBV) protein EBNA1, a critical factor in EBV's ability to transform human cells and cause cancer. Study provides new indications for inhibiting EBNA1 function, opening up fresh avenues for development of therapies to treat EBV-associated cancers. from Top Health News -- ScienceDaily https://ift.tt/394NoSR via IFTTT

Balancing brain cell activity

Electrical trigger sites in neurons surprisingly change with experience; they are either becoming smaller with increasing number of experiences and, vice versa, they grow larger when less input arrives in the brain. from Top Health News -- ScienceDaily https://ift.tt/3p9JVrT via IFTTT

See how they run: 'Exercise protein' doubles running capacity, restores function and extends healthy lifespans in older mice

A new study shows that humans express a powerful hormone during exercise and that treating mice with the hormone improves physical performance, capacity and fitness. Researchers say the findings present new possibilities for addressing age-related physical decline. from Top Health News -- ScienceDaily https://ift.tt/392CxJf via IFTTT

Tiny high-tech probes reveal how information flows across the brain

A new study collected and analyzed the largest single dataset of neurons' electrical activity to glean principles of how we perceive the visual world around us. The study captures the hundreds of split-second electrical signals that fire when an animal is interpreting what it sees. from Top Health News -- ScienceDaily https://ift.tt/39UHuD3 via IFTTT

The physics behind tumor growth

Researchers have developed a predictive theory for tumor growth that approaches the subject from a new point of view. Rather than focusing on the biological mechanisms of cellular growth, the researchers instead use thermodynamics and the physical space the tumor is expanding into to predict its evolution from a single cell to a complex cancerous mass. from Top Health News -- ScienceDaily https://ift.tt/3sMjL0z via IFTTT

CRISPR technology to cure sickle cell disease

A new article reports two patients appear to have been cured of beta thalassemia and sickle cell disease after their own genes were edited with CRISPR-Cas9 technology. The two researchers who invented this technology received the Nobel Prize in Chemistry in 2020. from Top Health News -- ScienceDaily https://ift.tt/361xnvf via IFTTT

Message in a bottle: Info-rich bubbles respond to antibiotics

Researchers describe the effects of antibiotics on membrane vesicles, demonstrating that such drugs actively modify the properties of vesicle transport. Under the influence of antibiotics, MVs were produced and released by bacteria in greater abundance and traveled faster and further from their origin. The work sheds new light on these important information-carrying entities, implicated in many cellular communication processes, including antibiotic resistance. from Top Health News -- ScienceDaily https://ift.tt/2LXrHeK via IFTTT

Estrogen receptors in mom's placenta critical during viral infection

A team of researchers has found a mechanism that protects a fetus from harm when the mother's innate immune system responds to a viral infection. Inflammation that would harm the fetus is dampened by a cell-surface estrogen receptor called GPER1 that is especially abundant in the placenta and fetal tissues. from Top Health News -- ScienceDaily https://ift.tt/3c0GHTT via IFTTT

Researchers ID potential target for anti-viral drugs to battle COVID

Researchers have published the first structural biology analysis of a section of the COVID-19 viral RNA called the stem-loop II motif. This is a non-coding section of the RNA, which means that it is not translated into a protein, but it is likely key to the virus's replication. from Top Health News -- ScienceDaily https://ift.tt/2Y3aLWQ via IFTTT

COVID-19 is dangerous for middle-aged adults, not just the elderly

COVID-19 has been spreading rapidly over the past several months, and the U.S. death toll has now reached 400,000. As evident from the age distribution of those fatalities, COVID-19 is dangerous not only for the elderly but for middle-aged adults, according to a new study. from Top Health News -- ScienceDaily https://ift.tt/3iy8X1v via IFTTT

A closer look at T cells reveals big differences in mild vs. severe COVID-19 cases

How long does immunity to SARS-CoV-2 last following infection? Researchers have uncovered an interesting clue. Their new study suggests that people with severe COVID-19 cases may be left with more of the protective 'memory' T cells needed to fight reinfection. from Top Health News -- ScienceDaily https://ift.tt/3qBubhy via IFTTT

Why older adults must go to the front of the vaccine line

A new global, mathematical modeling study shows that in most cases prioritizing older adults for COVID-19 vaccines saves the most lives. It also found that, in some cases, more lives could be saved and infections prevented if those who've already tested positive step to the back of the line. from Top Health News -- ScienceDaily https://ift.tt/3qDScEQ via IFTTT

COVID-19 infection in immunodeficient patient cured by infusing convalescent plasma, doctors report

Under FDA emergency-use authorization, doctors successfully resolved COVID-19 in a seriously ill, immunodeficient woman using a very high-neutralizing antibody-titer convalescent plasma from a recovered COVID-19 patient. However, further study suggested that use of convalescent plasma may not be warranted in many cases, for two reasons: 1) titer levels are too low in many convalescent plasmas, and 2) there are high endogenous neutralizing antibody titers already present in COVID-19 patients prior to infusion. from Top Health News -- ScienceDaily https://ift.tt/39PzAuY via IFTTT

Randomized trials could help to return children safely to schools, study finds

Schools are closing again in response to surging levels of COVID-19 infection, but staging randomized trials when students eventually return could help to clarify uncertainties around when we should send children back to the classroom, according to a new study. from Top Health News -- ScienceDaily https://ift.tt/2LLaCoA via IFTTT

Deep sleep takes out the trash

By examining fruit flies' brain activity and behavior, the researchers found that deep sleep has an ancient, restorative power to clear waste from the brain. This waste potentially includes toxic proteins that may lead to neurodegenerative disease. from Top Health News -- ScienceDaily https://ift.tt/3sJW3SL via IFTTT

Hematopoietic stem cell transplants may provide long-term benefit for people with MS

A new study shows that intense immunosuppression followed by a hematopoietic stem cell transplant may prevent disability associated with multiple sclerosis (MS) from getting worse in 71% of people with relapsing-remitting MS for up to 10 years after the treatment. The study also found that in some people their disability improved over 10 years after treatment. from Top Health News -- ScienceDaily https://ift.tt/3o2Kgez via IFTTT

Free online tool calculates risk of COVID-19 transmission in poorly-ventilated spaces

The vital role of ventilation in the spread of COVID-19 has been quantified by researchers, who have found that in poorly ventilated spaces, the virus spreads further than two meters in seconds, and is far more likely to spread through prolonged talking than through coughing. from Top Health News -- ScienceDaily https://ift.tt/35WHkKc via IFTTT

NAD+ can restore age-related muscle deterioration, research finds

Scientists have discovered that Alzheimer's-like protein aggregates underly the muscle deterioration seen in aging. But the aggregates can be reversed by boosting the levels of nicotinamide adenine dinucleotide (NAD+), which turns on the defense systems of mitochondria in cells and restores muscle function. from Top Health News -- ScienceDaily https://ift.tt/361ZTwS via IFTTT

Brain cell network supplies neurons with energy

Until recently, oligodendrocytes were primarily thought to be a kind of cellular insulating tape that accelerates the transmission of electrical signals in the brain. A study now shows that they are also important for the energy supply of neurons in some brain regions. from Top Health News -- ScienceDaily https://ift.tt/39024Tf via IFTTT

Age influences sex-related outcomes after heart attack

Approximately 1.5 million heart attacks and strokes occur every year in men and women in the US. Sex and age play a large part in who experiences a heart attack, the methods used to treat these heart attacks, and the eventual post hospital outcomes of the people who experience heart attacks. from Top Health News -- ScienceDaily https://ift.tt/2LSxeU3 via IFTTT

Fatty acid may help combat multiple sclerosis, study finds

The abnormal immune system response that causes multiple sclerosis (MS) by attacking and damaging the central nervous system can be triggered by the lack of a specific fatty acid in fat tissue, according to a new study. The finding suggests that dietary change might help treat some people with the autoimmune disease. from Top Health News -- ScienceDaily https://ift.tt/35RXwfS via IFTTT

Mental health conditions alarmingly high among children with autism, study finds

Nearly 78 per cent of children with autism have at least one mental health condition and nearly half have more than that, according to a new study. Mental health conditions were present in 44.8 per cent of pre-school age children with autism -- a group among which prevalence had not previously been established using a large, population-based sample. Only 14.1 per cent of children without autism (ages 3-17) had mental health conditions. from Top Health News -- ScienceDaily https://ift.tt/3bVpuvg via IFTTT

Prenatal BPA exposure may contribute to the male bias of autism spectrum disorder

Autism has a higher prevalence in males than females. Bisphenol A (BPA) is a common chemical found in plastics, our food, and even the human placenta. Higher prenatal exposure to BPA is thought to increase the risk of autism. Researchers have identified autism candidate genes that may be responsible for the sex-specific effects of BPA. from Top Health News -- ScienceDaily https://ift.tt/3bTxH2R via IFTTT

New method heals skeletal injuries with synthetic bone

Researchers have developed a way of combining a bone substitute and drugs to regenerate bone and heal severe fractures in the thigh or shin bone. The study was conducted on rats, but the researchers think that the method in various combinations will soon be commonplace in clinical settings. from Top Health News -- ScienceDaily https://ift.tt/3oXWUNe via IFTTT

Eye tests predict Parkinson's-linked cognitive decline 18 months ahead

Simple vision tests can predict which people with Parkinson's disease will develop cognitive impairment and possible dementia 18 months later, according to a new study. In a related study, the researchers also found that structural and functional connections of brain regions become decoupled throughout the entire brain in people with Parkinson's disease, particularly among people with vision problems. from Top Health News -- ScienceDaily https://ift.tt/3sFAP8E via IFTTT

A biological strategy reveals how efficient brain circuitry develops spontaneously

Researchers have explained how the regularly structured topographic maps in the visual cortex of the brain could arise spontaneously to efficiently process visual information. This research provides a new framework for understanding functional architectures in the visual cortex during early developmental stages. from Top Health News -- ScienceDaily https://ift.tt/3bSTQy9 via IFTTT

Money matters to happiness--perhaps more than previously thought

Money matters to happiness, perhaps more so than previously thought, according to new research. One potential reason: Higher earners feel an increased sense of control over life. 'Across decisions big and small, having more money gives a person more choices and a greater sense of autonomy,' he says. from Top Health News -- ScienceDaily https://ift.tt/2LMdwJx via IFTTT

Childhood neglect leaves generational imprint

Early life experiences can have an outsized effect on brain development and neurobiological health. New research is showing that those effects can be passed down to subsequent generations, reporting that the infant children of mothers who had experienced childhood emotional neglect displayed altered brain circuitry involved in fear responses and anxiety. from Top Health News -- ScienceDaily https://ift.tt/39I8buU via IFTTT

Successive governments' approach to obesity policies has destined them to fail

Government obesity policies in England over the past three decades have largely failed because of problems with implementation, lack of learning from past successes or failures, and a reliance on trying to persuade individuals to change their behavior rather than tackling unhealthy environments. from Top Health News -- ScienceDaily https://ift.tt/3nWafo8 via IFTTT

Rapid blood test identifies COVID-19 patients at high risk of severe disease

Scientists have shown that a relatively simple and rapid blood test can predict which patients with COVID-19 are at highest risk of severe complications or death. The blood test measures levels of mitochondrial DNA, which normally resides inside the energy factories of cells. Mitochondrial DNA spilling out of cells and into the bloodstream is a sign that a particular type of violent cell death is taking place in the body. from Top Health News -- ScienceDaily https://ift.tt/35Rdjvy via IFTTT

Personalized brain stimulation alleviates severe depression symptoms

Targeted neuromodulation tailored to individual patients' distinctive symptoms is an increasingly common way of correcting misfiring brain circuits in people with epilepsy or Parkinson's disease. Now, scientists have demonstrated a novel personalized neuromodulation approach that -- at least in one patient -- was able to provide relief from symptoms of severe treatment-resistant depression within minutes. from Top Health News -- ScienceDaily https://ift.tt/2LKbxVZ via IFTTT

Synthesis of potent antibiotic follows unusual chemical pathway

Images of a protein involved in creating a potent antibiotic reveal the unusual first steps of the antibiotic's synthesis. The improved understanding of the chemistry behind this process could allow researchers to adapt this and similar compounds for use in human medicine. from Top Health News -- ScienceDaily https://ift.tt/2KrgGSp via IFTTT

Scientists reveal mechanism that causes irritable bowel syndrome

Researchers have identified the biological mechanism that explains why some people experience abdominal pain when they eat certain foods. The finding paves the way for more efficient treatment of irritable bowel syndrome and other food intolerances. The study was carried out in mice and humans. from Top Health News -- ScienceDaily https://ift.tt/38SgDZ5 via IFTTT

One small alcoholic drink a day is linked to an increased risk of atrial fibrillation

A study of nearly 108,000 people has found that people who regularly drink a modest amount of alcohol are at increased risk of atrial fibrillation, a condition where the heart beats in an abnormal rhythm. The study found that, compared to drinking no alcohol at all, just one alcoholic drink a day was linked to a 16% increased risk of atrial fibrillation over an average follow-up time of nearly 14 years. from Top Health News -- ScienceDaily https://ift.tt/2LWLk6D via IFTTT

Scientists identify nutrient that helps prevent bacterial infection

Scientists studying the body's natural defenses against bacterial infection have identified a nutrient -- taurine -- that helps the gut recall prior infections and kill invading bacteria, such as Klebsiella pneumoniae (Kpn). The finding could aid efforts seeking alternatives to antibiotics. from Top Health News -- ScienceDaily https://ift.tt/2XJ6Ga3 via IFTTT

Researchers discover new inhibitor drug combination for rare form of cancer

Researchers took the novel approach of targeting specific cell proteins that control DNA information using inhibitors, or drugs, that were effective in reducing the growth of the Waldenström macroglobulinemia cancer cells and when combined with a third drug were even more successful in killing the WM cancer cells which could lead to more treatment options. from Top Health News -- ScienceDaily https://ift.tt/2LEg9gv via IFTTT

RNA's mysterious folding process

Using data from RNA-folding experiments, the researchers generated the first-ever data-driven movies of how RNA folds as it is made by cellular machinery. By watching their videos of this folding occur, the researchers discovered that RNA often folds in surprising, perhaps unintuitive ways, such as tying itself into knots. from Top Health News -- ScienceDaily https://ift.tt/3oZZWQY via IFTTT

Breathing easier with a better tracheal stent

New research is poised to drastically improve the use of tracheal stents for children with airway obstruction. Researchers demonstrate for the first time the successful use of a completely biodegradable magnesium-alloy tracheal stent that safely degrades and does not require removal. from Top Health News -- ScienceDaily https://ift.tt/3oNwKfX via IFTTT

Increased risk of Parkinson's disease in patients with schizophrenia

A new study shows that patients with a schizophrenia spectrum disorder have an increased risk of Parkinson's disease later in life. The increased risk may be due to alterations in the brain's dopamine system caused by dopamine receptor antagonists or neurobiological effects of schizophrenia. from Top Health News -- ScienceDaily https://ift.tt/3oPO9op via IFTTT

Researchers Find NTRK fusions more common than expected in pediatric tumors

Researchers have found that NTRK fusions are more common in pediatric tumors and also involve a wider range of tumors than adult cancers, information that could help prioritize screening for NTRK fusions in pediatric cancer patients who might benefit from treatment with TRK inhibitors. from Top Health News -- ScienceDaily https://ift.tt/3nKgrzj via IFTTT

ADA lowers target HbA1C levels for children with type-1 diabetes

In early 2020, upon recommendation by leading endocrinologists, American Diabetes Association lowered the target hemoglobin A1C guidelines for children with type 1 diabetes. Their goal in recommending stricter glucose control was to ensure children with type 1 diabetes have better immediate and long-term health outcomes with fewer health complications and reduced mortality rates. Researchers now discuss the evidence and rationale behind this new recommendation. from Top Health News -- ScienceDaily https://ift.tt/2XIj4qP via IFTTT

Acute itching in eczema patients linked to environmental allergens

New research indicates that allergens in the environment often are to blame for episodes of acute itch in eczema patients, and that the itching often doesn't respond to antihistamines because the itch signals are being carried to the brain along a previously unrecognized pathway that current drugs don't target. from Top Health News -- ScienceDaily https://ift.tt/3oNtNw8 via IFTTT

Scientists uncover new path toward treating a rare but deadly neurologic condition

Molybdenum cofactor (Moco) is a compound that is little known but is essential for life. Children born without the ability to synthesize Moco die young. It has not been possible to create Moco supplements because the compound is so unstable. Studies in the nematode Caenorhabditis elegans suggest that by combining, Moco with certain proteins, it becomes stable and can repair deficiency. from Top Health News -- ScienceDaily https://ift.tt/3bIkEBh via IFTTT

Scholars link diet, dentition, and linguistics

Anthropologists used a novel data analysis of thousands of languages, in addition to studying a unique subset of celebrities, to reveal how a soft food diet -- contrasted with the diet of hunter-gatherers -- is restructuring dentition and changing how people speak. from Top Health News -- ScienceDaily https://ift.tt/38KBzkB via IFTTT

The role of T cells in fighting cancer

Why do some hosts' immune systems reject tumors easily, while others have a harder time doing so? It depends on the types of the immune cells known as CD8 T cells and how a host's specific T cells match up with the neoantigens present in the tumor. from Top Health News -- ScienceDaily https://ift.tt/3nLGFl7 via IFTTT

Research breaks new ground in understanding how a molecular motor generates force

A team of biophysicists set out to tackle the long-standing question about the nature of force generation by myosin, the molecular motor responsible for muscle contraction. The key question they addressed - one of the most controversial topics in the field - was: how does myosin convert chemical energy, in the form of ATP, into mechanical work? The answer revealed new details into how myosin, the engine of muscle and related motor proteins, transduces energy. from Top Health News -- ScienceDaily https://ift.tt/35FGVM3 via IFTTT

Feces and algorithms: Artificial Intelligence to map our intestinal bacteria

The intestines and their bacteria are sometimes called our 'second brain', but studying these bacteria in their natural environment is difficult. Now researchers have developed a method that uses artificial intelligence to map intestinal bacteria using feces. The researchers thus hope to gain more knowledge of the role played by these bacteria in various diseases. from Top Health News -- ScienceDaily https://ift.tt/2LSbZkI via IFTTT

Physical virology shows the dynamics of virus reproduction

The reproductive cycle of viruses requires self-assembly, maturation of virus particles and, after infection, the release of genetic material into a host cell. New physics-based technologies allow scientists to study the dynamics of this cycle and may eventually lead to new treatments. from Top Health News -- ScienceDaily https://ift.tt/3nKFMcn via IFTTT

Acting quickly after heart attack symptoms start can be a heart saver

The degree of heart muscle damage from a heart attack is associated with how long it takes from when heart attack symptoms start to when patients receive an artery-clearing procedure called percutaneous coronary intervention, or PCI. The longer the time period before PCI, called symptom-to-balloon time, the more significant and damaging the heart attack. from Top Health News -- ScienceDaily https://ift.tt/2KdIg5o via IFTTT

SolarEV City concept: Building the next urban power and mobility systems

Cities are responsible for 60-70% of energy-related CO2 emissions. As the world is increasingly urbanized, it is crucial to identify cost-effective pathways to decarbonize. Here, we propose a ''SolarEV City'' concept, in which integrated systems of cities' roof-top PVs with EVs as batteries can supply affordable and dispatchable CO2-free electricity for citie's dwerllers, which can reduce CO2 emission by 54-95% with 26-41% of potential cost savings by 2030. from Top Health News -- ScienceDaily https://ift.tt/2LwDEIg via IFTTT