Skip to main content

Posts

Showing posts from August, 2021

Early warning signals could help monitor disease outbreaks

New research suggests early warning signals (EWSs) could help in the monitoring of disease outbreaks, such as COVID-19. The study found warnings could be detected weeks earlier than any rapid increase in cases. The findings could help governments and policy makers improve the accuracy of their decisions and allow timely interventions if needed. from Top Health News -- ScienceDaily https://ift.tt/3DvxDk4 via IFTTT

Biomarkers found for COVID-19 condition in children

A rare but serious inflammatory condition that affects children who contract COVID-19 produces a distinctive pattern of biomarkers that may help physicians predict disease severity and also aid researchers in developing new treatments, according to a new study. from Top Health News -- ScienceDaily https://ift.tt/3kKgyv8 via IFTTT

Ferroelectrics everywhere?

A new family of materials that could result in improved digital information storage and uses less energy may be possible thanks to a team of researchers who demonstrated ferroelectricity in magnesium-substituted zinc oxide. from Top Health News -- ScienceDaily https://ift.tt/3mWqvbA via IFTTT

Researchers discover way to switch on and speed up tendon healing

A research team investigated whether electrical therapy, coupled with exercise, would show promise in treating tendon disease or ruptures. They found that tendon cell function and repair can be controlled through electrical stimulation from an implantable device powered by body movement. from Top Health News -- ScienceDaily https://ift.tt/3BrByOb via IFTTT

In a common genetic disorder, blood test reveals when benign tumors turn cancerous

Researchers have developed a blood test that, they believe, could one day offer a highly sensitive and inexpensive approach to detect cancer early in people with NF1. The blood test could also help doctors monitor how well patients are responding to treatment for their cancer. from Top Health News -- ScienceDaily https://ift.tt/3zzNb51 via IFTTT

Fighting brain cancer at its root

Researchers identify proteins that drive cancer stem cells. Targeting and suppressing a particular protein called galectin1 could provide a more effective treatment for glioblastoma, in combination with radiation therapy. from Top Health News -- ScienceDaily https://ift.tt/3yAFQRo via IFTTT

How to produce proteins at the right speed

In all eukaryotic organisms, genetic material is stored in the cell nucleus in the form of DNA. In order to be used, this DNA is first transcribed into messenger RNA in the cell cytoplasm, then translated into protein with the help of ribosomes, small machines capable of decoding messenger RNA to synthesize the appropriate proteins. However, the speed with which this mechanism takes place is not uniform: it must adapt to allow the protein to adopt the right configuration. Indeed, a deregulation of the production rate leads to structural defects. The proteins, which are not correctly folded will aggregate, become unusable and often toxic for the cell. from Top Health News -- ScienceDaily https://ift.tt/3yytIR5 via IFTTT

Genomic data reveals new insights into human embryonic development

Genomic scientists have revealed new insights into the process of human embryonic development using large-scale, whole-genome sequencing of cells and tissues from adult humans. The study analyzes somatic mutations in normal tissue across multiple organs within and between humans. from Top Health News -- ScienceDaily https://ift.tt/3DAE8U0 via IFTTT

High virus count in the lungs drives COVID-19 deaths, study finds

A buildup of coronavirus in the lungs is likely behind the steep mortality rates seen in the pandemic, a new study finds. The results contrast with previous suspicions that simultaneous infections, such as bacterial pneumonia or overreaction of the body's immune defense system, played major roles in heightened risk of death, the investigators say. from Top Health News -- ScienceDaily https://ift.tt/3Bx3dxl via IFTTT

Genes can respond to coded information in signals – or filter them out entirely

Researchers have demonstrated that genes are capable of identifying and responding to coded information in light signals, as well as filtering out some signals entirely. The study shows how a single mechanism can trigger different behaviors from the same gene. from Top Health News -- ScienceDaily https://ift.tt/3BvmjUC via IFTTT

Do distressed, help-seeking couples improve on their own? Not much, study says

Does relationship quality continue to worsen, stabilize, or improve for distressed, help-seeking couples before they receive assistance? A team of researchers sought to answer that question in a new study examining what happens to couples who seek online help for their relationship, but have to wait six months before beginning an intervention program. from Top Health News -- ScienceDaily https://ift.tt/2WypVq4 via IFTTT

Bystander CPR with rescue breathing leads to better outcomes in pediatric cardiac arrest: Study

When children and adolescents go into cardiac arrest outside of a hospital setting, CPR with rescue breathing -- rather than CPR using only chest compressions -- leads to better outcomes, according to a new study. The findings support the use of bystander CPR with rescue breathing in children experiencing cardiac arrest. from Top Health News -- ScienceDaily https://ift.tt/3Bs6UEp via IFTTT

Reliable oxygenation conceivable with new design for portable concentrators

Anticipating the increased need for better oxygen concentrators as the fight against COVID-19 rages on, researchers have laid a computational framework to design the most optimal concentrator to filter ambient air and produce oxygen that can scale with patient demand. from Top Health News -- ScienceDaily https://ift.tt/3sZ8B9i via IFTTT

How people respond to wildfire smoke

Interviews with Northern California residents reveal that social norms and social support are essential for understanding protective health behaviors during wildfire smoke events -- information that could be leveraged to improve public health outcomes. from Top Health News -- ScienceDaily https://ift.tt/3yz0rWi via IFTTT

How a racing heart may alter decision-making brain circuits

In an effort to understand how the internal state of the body influences the brain's decision-making processes, scientists analyzed the data from a previous study pre-clinical study. They found that two of the brain's decision-making centers contain neurons that may exclusively monitor the body's internal dynamics. Furthermore, a heightened state of arousal appeared to rewire one of the centers by turning some decision-making neurons into internal state monitors. from Top Health News -- ScienceDaily https://ift.tt/3DyXHvG via IFTTT

At least 80% of opioid overdoses aren’t fatal, but how do they affect the brain?

Scientists still know little about how opioid overdoses affect the brain and cognition. Researchers found that, while evidence exists to support a link between overdose, cognitive impairment and brain abnormalities, more research is needed in this area. from Top Health News -- ScienceDaily https://ift.tt/3gIVh3O via IFTTT

AI helps to spot single diseased cells

Researchers developed a novel artificial intelligence algorithm for clinical applications called 'scArches'. It efficiently compares patients' cells with a reference atlas of cells of healthy individuals. This enables physicians to pinpoint cells in disease and prioritize them for personalized treatment in each patient. from Top Health News -- ScienceDaily https://ift.tt/3yuOkJG via IFTTT

Researchers identify new biomarkers to detect consumption of emerging illicit drug

A team of researchers has come up with a new solution to boost the surveillance of designer drug abuse. The team has identified three new urinary biomarkers that could be used to detect consumption of ADB-BUTINACA, an emerging synthetic cannabinoid which is a type of new psychoactive substance. The innovative approach used to identify the biomarkers can be applied to other existing and new synthetic cannabinoids. from Top Health News -- ScienceDaily https://ift.tt/3ysenBp via IFTTT

One in two pregnancies are affected by iron deficiency, yet many women don’t get a simple screening test to check

Half of pregnant women who had a simple blood test to check their iron stores had low iron levels, and one in four had severe iron deficiency, according to a new article. But despite how common iron deficiency is, 40% of pregnant women in this large regional study never had their iron levels checked, and women of lower socioeconomic status were less likely to get tested. Researchers said the findings underscore the need to revisit clinical guidelines to ensure that ferritin testing, the standard measure of iron deficiency, is included as a routine part of maternal care and pregnancy health screenings. from Top Health News -- ScienceDaily https://ift.tt/3juCknC via IFTTT

Unease beyond the uncanny valley: How people react to the same faces

If humanoid robots with the same appearance are mass-produced and become commonplace, how will human beings react to them? In a series of six experiments, scientists examined peoples' reactions when presented with images of people with the same face. Their results reveal a new phenomenon they call the clone devaluation effect -- a greater eeriness associated with cloned faces than with different faces. from Top Health News -- ScienceDaily https://ift.tt/3jq4ShM via IFTTT

Finerenone improves outcomes in patients with mild-to-moderate kidney disease and diabetes

Finerenone reduces the risk of cardiovascular morbidity and mortality in patients with mild-to-moderate kidney disease and type 2 diabetes. Diabetic kidney disease develops in approximately 40% of patients with diabetes and is the leading cause of chronic kidney disease worldwide. Some patients progress to end-stage renal disease, but most die from cardiovascular diseases and infections before needing kidney replacement therapy. from Top Health News -- ScienceDaily https://ift.tt/38oaMto via IFTTT

Increased survival with eye melanoma in clinical trial

Once it has spread (metastasized), uveal (intraocular or eye) melanoma -- an unusual form of cancer -- has a very high mortality rate. Researchers and doctors show that, in a small group of patients with metastatic uveal melanoma, a new combination treatment can bring about tumor shrinkage and prolonged survival. from Top Health News -- ScienceDaily https://ift.tt/3Du17Qm via IFTTT

How can I avoid heart disease or stroke?

As much as 90% of the risk of a heart attack, stroke, or peripheral arterial disease (PAD) can be explained by smoking, poor eating habits, lack of physical activity, abdominal obesity, high blood pressure, raised blood lipid levels, diabetes, psychosocial factors, or alcohol. These guidelines focus on atherosclerotic cardiovascular disease (CVD), which affects the arteries. As the inside of the arteries become clogged up by fatty deposits, they can no longer supply enough blood to the body. This process is the main cause of heart attacks, strokes, PAD and sudden death where arteries become completely blocked. The most important way to prevent these conditions is to adopt a healthy lifestyle throughout life, especially not smoking, and to treat risk factors. from Top Health News -- ScienceDaily https://ift.tt/3gIPQC2 via IFTTT

Monoclonal antibody treatment combo reduces hospitalization among high-risk patients with COVID-19

In an observational study, researchers report that the combination of casirivimab and imdevimab -- two monoclonal antibody treatments under Food and Drug Administration emergency use authorization -- keep high-risk patients out of the hospital when infected with mild to moderate COVID-19. from Top Health News -- ScienceDaily https://ift.tt/3gILcnA via IFTTT

COVID-19 antibody study shows downside of not receiving second shot

A new study shows that two months after the second Pfizer/Moderna vaccination, antibody response decreases 20 percent in adults with prior cases of COVID-19, and tests how well current vaccines resist emerging variants. The study also showed that prior exposure to SARS-CoV-2 does not guarantee a high level of antibodies, nor does it guarantee a robust antibody response to the first vaccine dose. This directly contradicts the assumption that contracting COVID will naturally make someone immune to re-infection. The findings further support vaccination (and two doses), even for people who have contracted the virus previously. from Top Health News -- ScienceDaily https://ift.tt/3kAVYO3 via IFTTT

Staying home, having access to primary care, and limiting contagion hubs may curb COVID-19 deaths

Staying home and limiting local travel, supporting access to primary care, and limiting contacts in contagion hubs -- including hospitals, schools, and workplaces -- are strategies that might help reduce COVID-19-related deaths, according to new research that analyzed the first wave of the epidemic in Italy. from Top Health News -- ScienceDaily https://ift.tt/3DnrCaa via IFTTT

Four-in-one blood pressure pill: Safe and much more effective than usual hypertension treatment, study finds

The first large-scale, long-term trial of a new strategy using combinations of very low-doses in one capsule, has demonstrated significantly improved control of high blood pressure -- the leading cause of heart attack and stroke. from Top Health News -- ScienceDaily https://ift.tt/3jsVOZN via IFTTT

Want to play college sports? A wealthy family helps

It takes more than athletic talent to play varsity sports in college, at least for most young people, a new study suggests. Researchers found that U.S. high-school athletes were much more likely to play sports in college if they came from higher-income families with well-educated parents and attended wealthier schools. from Top Health News -- ScienceDaily https://ift.tt/3zvQ9rd via IFTTT

Eating walnuts daily lowered 'bad' cholesterol and may reduce cardiovascular disease risk

Healthy older adults who ate a handful of walnuts (about ½ cup) a day for two years modestly lowered their level of low-density lipoprotein or LDL cholesterol levels. Consuming walnuts daily also reduced the number of LDL particles, a predictor of cardiovascular disease risk. The study explored the effects of a walnut-enriched diet on overall cholesterol in elderly individuals from diverse geographical locations and spanning two years. from Top Health News -- ScienceDaily https://ift.tt/38r8Noc via IFTTT

Old habit-controlling neurons may also help the brain learn new tricks

In a study of rodents, scientists discovered that a part of the brain traditionally thought to control typing the old sequence may also play a critical role in learning the new one. The results suggest that this process involves a delicate balance in the activity of two neighboring neural circuits: one dedicated to new actions and the other to old habits. from Top Health News -- ScienceDaily https://ift.tt/38o6vGq via IFTTT

Your sense of smell may be the key to a balanced diet

When we smell food, we are more likely to eat -- but new findings suggest eating food also impacts our sense of smell, which could bias what we eat next. Imaging shows that brain's response to odors similar to a recent meal is less 'food-like' than its response to a different food odor. Interplay between smell and food intake may have evolutionary benefit in helping humans diversify diet from Top Health News -- ScienceDaily https://ift.tt/3BnMuMW via IFTTT

Environmental pollution may contribute to racial/ethnic disparities In Alzheimer’s disease risk

Fine particle pollution may be one reason why Black women have double the risk of developing Alzheimer's than white women, suggests new research. Data shows that older people are more likely to develop dementia if they live in locations with high PM2.5, and African American populations are more likely to live in neighborhoods near polluting facilities. Even when controlling for other risk factors, this study found that Black women still had roughly two times greater a risk of developing Alzheimer's disease than white women, and it also found that they had higher exposure to PM2.5. from Top Health News -- ScienceDaily https://ift.tt/2WxnnIr via IFTTT

Embryonic development in slow motion

Roe deer are among the few mammals whose embryos go into a particularly long period of dormancy. Using modern molecular methods, researchers have shown for the first time what exactly happens in the embryo during this phase. They have identified signals that control the embryo`s awakening. from Top Health News -- ScienceDaily https://ift.tt/38iipl4 via IFTTT

Simple safety measures reduce musical COVID-19 transmission

Researchers have found that while playing musical instruments can emit the same levels of potentially COVID-laden airborne particles as singing, simple safety measures, such as masking instruments, social distancing and implementing time limits, significantly reduce this risk. from Top Health News -- ScienceDaily https://ift.tt/3zuztRa via IFTTT

Study confirms virus variants reduce protection against COVID-19

A laboratory study finds that blood serum drawn from people previously vaccinated or naturally infected show 'significantly reduced' defense against two variants of the novel coronavirus SARS-CoV-2. Researchers said that their findings emphasize the importance of vaccinations combined with maintaining public health measures to cut off the spread of the SARS-CoV-2 virus. from Top Health News -- ScienceDaily https://ift.tt/3kAJaHw via IFTTT

Diverse DNA signatures linked to heart disease

Risk for heart disease does not look the same on the genetic level for different population groups, report an international team of researchers. The studY begins to outline gene activity patterns that could serve as early warning indicators for cardiovascular disease. from Top Health News -- ScienceDaily https://ift.tt/3jqcIIx via IFTTT

Study identifies 579 genetic locations linked to anti-social behavior, alcohol use, opioid addiction and more

An analysis of data from 1.5 million people has identified 579 locations in the genome associated with a predisposition to different behaviors and disorders related to self-regulation, including addiction and child behavioral problems. from Top Health News -- ScienceDaily https://ift.tt/38vwrQN via IFTTT

Restoring 'chaperone' protein may prevent plaque build-up in Alzheimer’s

Researchers have shown how restoring levels of the protein DAXX and a large group of similar proteins prevents the misfolding of the rogue proteins known to drive Alzheimer's and other neurodegenerative diseases, as well as certain mutations that contribute to cancers. from Top Health News -- ScienceDaily https://ift.tt/2Ws2Gha via IFTTT

Research supports FDA recommendation: Patients with implanted medical devices should keep their smart phones and watches at least six inches away

A new study supports the FDA recommendation that patients keep any consumer electronic devices that may create magnetic interference, including cell phones and smart watches, at least six inches away from implanted medical devices, in particular pacemakers and cardiac defibrillators. from Top Health News -- ScienceDaily https://ift.tt/2UVFTcY via IFTTT

One in three Americans had COVID-19 by the end of 2020, study estimates

A new study estimates that 103 million Americans, or 31 percent of the U.S. population, had been infected with SARS-CoV-2 by the end of 2020. Researchers modeled the spread of the coronavirus, finding that fewer than one-quarter of infections (22 percent) were accounted for in cases confirmed through public health reports based on testing. from Top Health News -- ScienceDaily https://ift.tt/3jk1MvW via IFTTT

Secrets of COVID-19 transmission revealed in turbulent puffs

Researchers have developed a new model that explains how turbulent puffs, like coughs, behave under different environmental conditions. They found that at environmental temperatures 15°C or lower, the puffs behaved with newly observed dynamics, showing more buoyancy and traveling further. Their findings could help scientists better predict how turbulence and the environment affect airborne transmission of viruses like SARS-CoV-2. from Top Health News -- ScienceDaily https://ift.tt/3DjKTcG via IFTTT

Call for healthcare leaders to ensure women and girls have access to safe and affordable menstrual products and health

A new commentary reinforces the need to engage the public in understanding the importance of menstrual health. This includes sufficient funding and more research to educate young people, their parents and communities about the process of menstruation, along with the clinicians who serve them. from Top Health News -- ScienceDaily https://ift.tt/3gAxi72 via IFTTT

COVID-19 is most transmissible 2 days before and 3 days after symptoms appear

A new study has found that individuals infected with the COVID-19 virus are most contagious two days before, and three days after, they develop symptoms. The study also finds that infected individuals are more likely to be asymptomatic if they contracted the virus from someone who was asymptomatic. from Top Health News -- ScienceDaily https://ift.tt/3ji8NwZ via IFTTT

Men and women of Roman Herculaneum had different diets, new research shows

Archaeologists examining the Herculaneum skeletal remains of the victims of Vesuvius say they have helped shed new light on the eating habits of ancient Romans -- with food differentiated along gender lines and revealing women ate more animal products and locally grown fruit and vegetables while the men dined on more expensive fish. from Top Health News -- ScienceDaily https://ift.tt/3mAiQj3 via IFTTT

Biomarker may help predict benefits of immunotherapy

A group of researchers reported that a specific pattern, or 'signature,' of markers on immune cells in the blood is a likely biomarker of response to checkpoint immunotherapy. Within this immune signature, a molecule LAG-3 provided key information identifying patients with poorer outcomes. from Top Health News -- ScienceDaily https://ift.tt/3mB2xmk via IFTTT

MOGONET provides more holistic view of biological processes underlying disease

To fully utilize the advances in omics technologies to achieve a more comprehensive understanding of the biological processes underlying human diseases, researchers have developed and tested MOGONET, a novel multi-omics data analysis algorithm and computational methodology. Integrating data from various omics provides a more holistic view of biological processes underlying human diseases. The creators have made MOGONET open source, free and accessible to all researchers. from Top Health News -- ScienceDaily https://ift.tt/3zjI1tO via IFTTT

Potentially safer approach to opioid drug development

Opioids are powerful painkillers but their use is hindered because patients become tolerant to them, requiring higher and higher doses, and overdoses can cause respiratory depression and death. A recent study contradicts existing thinking about how opioid drugs cause tolerance and respiratory depression, and suggests a new, balanced approach to developing safer analgesics. from Top Health News -- ScienceDaily https://ift.tt/3sOXBeq via IFTTT

Widespread tumor suppression mechanism stops cancer progression by interfering with cancer cell metabolism

A Wistar study shows the tumor suppressor Parkin, whose levels are reduced in different cancer types, causes acute metabolic and oxidative stress, suppresses mitochondrial trafficking, and blocks tumor cell movement, reducing primary and metastatic tumor growth. from Top Health News -- ScienceDaily https://ift.tt/2WpKlkk via IFTTT

Researchers identify genetic cause of endometriosis and reveal potential drug target

New research offers insight into how to treat endometriosis. The researchers performed genetic analyses of humans and rhesus macaques to identify a specific gene, NPSR1, that increases risk of suffering from endometriosis. The results reveal a potential new nonhormonal drug target that may lead to improved therapy. from Top Health News -- ScienceDaily https://ift.tt/38eIqSo via IFTTT

Add it up: Could this test equal a way to determine dementia risk?

People whose scores on a dementia risk test indicated a less brain-healthy lifestyle, including smoking, high blood pressure and a poor diet, may also have the following: lower scores on thinking skills tests, more changes on brain scans and a higher risk of cognitive impairment, according to a new study. from Top Health News -- ScienceDaily https://ift.tt/3DgzNVH via IFTTT

New research finds gender differences in fear and risk perception during COVID-19

New research suggests that men and women worry about the impact of COVID-19 in far different ways. For example, men are more likely to be concerned about financial consequences from COVID-19 while women report greater fear and more negative expectations about health-related outcomes. from Top Health News -- ScienceDaily https://ift.tt/3yivVzN via IFTTT

Baby detector software embedded in digital camera rivals ECG

Facial recognition is now common in adults, but researchers have developed software that can reliably detect a premature baby's face in an incubator and remotely monitor its heart and breathing rates - rivaling ECG machines and even outperforming them. This is the first step in using non-contact monitoring in neonatal wards, avoiding skin tearing and potential infections from adhesive pads. from Top Health News -- ScienceDaily https://ift.tt/3kmcYHD via IFTTT

Psychological capital may be the antidote for working in a pandemic, study suggests

Just like the COVID-19 vaccine protects against contracting the contagious virus, the collective elements of self-efficacy, optimism, hope and resiliency helps inoculate employees from the negative effects of working through a pandemic, according to a new study. from Top Health News -- ScienceDaily https://ift.tt/3krVBVE via IFTTT

Portable MRI provides life-saving information to doctors treating strokes

When patients exhibit stroke symptoms, doctors must quickly make a life or death determination: Are their symptoms caused by a clot that can be treated with blood thinners or by bleeding in the brain, which may require surgery? A new study shows that a portable MRI device can help identify such intracranial hemorrhages, potentially life-saving information particularly in areas or scenarios where access to sophisticated brain imaging scans are not readily available. from Top Health News -- ScienceDaily https://ift.tt/3yi2u0X via IFTTT

Teaching an old dog new tricks: An existing drug opens new possibilities for treating childhood leukemia

A new study has shown that the tumor-inhibiting gene TET2 is silenced in a large fraction of cases of acute lymphoblastic leukemia (ALL) in children. The scientists show that the gene can be reactivated by treatment with an existing drug, 5-azacytidine. The results suggest that 5-azacytidine may function as targeted therapy for ALL in children. from Top Health News -- ScienceDaily https://ift.tt/3kiGNJ4 via IFTTT

Evolutionary ‘arms race’ may help keep cell division honest

Certain proteins may have evolved to tamp down 'cheating' during meiosis, the cell-division process that gives rise to eggs and sperm. While chromosomes can tip the scales in their favor of winding up in an egg, the team's new work identifies a mechanism that keeps the odds closer to 50-50, possibly reducing the likelihood that chromosomal abnormalities will arise during egg production. from Top Health News -- ScienceDaily https://ift.tt/3yiv0PM via IFTTT

There’s a bright side to being a ‘Debbie Downer’

New research shows that keeping busy with a variety of activities can elicit both positive and negative emotions, and some of the relationship could depend on your age. A new study finds that engaging in diverse daily activities is associated with a diverse set of emotions. from Top Health News -- ScienceDaily https://ift.tt/2XW2nvt via IFTTT

A novel gene involved in male infertility: ZFP541

A new gene that controls the completion of meiosis in spermatogenesis has been discovered. Until now, details of the mechanism that inactivates the expression of genes involved in the meiotic program during spermatogenesis had not been clarified. The researchers believe that this may lead to an advancement in reproductive medicine, like identifying causes for infertility from azoospermia or spermatogenic defects. from Top Health News -- ScienceDaily https://ift.tt/2WqF2Bu via IFTTT

Stressed teens benefit from coping online, but a little goes a long way

An adolescent's day can be filled with a dizzying array of digital technologies. For many teenagers, being online is a way to pass the time and communicate with friends. Cell phones and social media can also help teens cope with stressful events -- as long as they strike the right balance between spending time online and pursuing other coping activities. from Top Health News -- ScienceDaily https://ift.tt/3zaFAK2 via IFTTT

Farmed carnivores may become 'disease reservoirs' posing human health risk

Carnivorous animals lack key genes needed to detect and respond to infection by pathogens, a study has found. Farming large numbers of carnivores, like mink, could allow the formation of undetected 'disease reservoirs', in which a pathogen could spread to many animals and mutate to become a risk to human health. from Top Health News -- ScienceDaily https://ift.tt/3zdVuDx via IFTTT

Viruses leave traces long after infection, research finds

Viruses do not always kill the cells they infect. Researchers have discovered in experiments with mice that cells have the power to self-heal and eliminate viruses. However, these cells undergo long-term changes. The findings may provide a hint as to why cured hepatitis C patients are more susceptible to liver cancer for years after. from Top Health News -- ScienceDaily https://ift.tt/2XI22wb via IFTTT

Male Y chromosome facilitates the evolution of sex differences in body size

Females and males differ in many ways and yet they share the same genome. The only exception is the male Y chromosome. Using beetles as a study system, new research shows that despite of the Y chromosome containing very few genes, it can dramatically change male body size and thus facilitate the evolution of sex differences. from Top Health News -- ScienceDaily https://ift.tt/3sJdIKu via IFTTT

Age-related decline in two sirtuin enzymes alters mitochondrial dynamics, weakens cardiac contractions

The potential protective effect of sirtuin enzymes in age-related diseases, including cardiovascular diseases, remains an area of intense investigation. Now, researchers has determined that sirtuin 1 (SIRT1) and sirtuin 3 (SIRT3) levels decline in aging hearts, disrupting the ability of cardiac muscle cells (cardiomyocytes) to contract in response to ischemia-reperfusion injury. from Top Health News -- ScienceDaily https://ift.tt/3motZUe via IFTTT

Reversal of lung fibrosis in mouse model suggests a novel therapeutic target for pulmonary fibrosis

Researchers have reversed lung fibrosis in a mouse model of idiopathic pulmonary fibrosis. Mice were given bleomycin for 12 days to establish lung fibrosis, and then treated daily until 21 days with ABT-199, whose medical form is known as Venetoclax, a medication approved by the United States Food and Drug Administration for use in several forms of leukemia. Control bleomycin mice had lung fibrosis with widespread collagen deposition. The bleomycin mice that received ABT-199 had normal lung architecture at 21 days and no collagen deposition. These results suggest a novel therapeutic target to reverse fibrotic remodeling in the lungs. from Top Health News -- ScienceDaily https://ift.tt/2UOr1Nu via IFTTT

Statistics say large pandemics are more likely than we thought

The COVID-19 pandemic may be the deadliest viral outbreak the world has seen in more than a century. But statistically, such extreme events aren't as rare as we may think, asserts a new analysis of novel disease outbreaks over the past 400 years. A newly assembled record of past outbreaks was used to estimate the probability of a pandemic with similar impact to COVID-19 is about 2 percent in any year. And that probability is growing. from Top Health News -- ScienceDaily https://ift.tt/3kfoLHE via IFTTT

Lagging chromosomes among causes of infertility

Why do women over 35 have more difficulty getting pregnant? After discovering one of the causes of age-related female infertility, researchers suggest that it will be possible in the future to improve the quality of the eggs of older patients by intervening on the cell cycle level. from Top Health News -- ScienceDaily https://ift.tt/3jdH7tj via IFTTT

Blueprints for how human kidneys form their filtering units

A team of scientists has conducted a comprehensive analysis reconstructing how kidneys form their filtering units, known as nephrons. The team studied hundreds of human and mouse nephrons at various points along their typical developmental trajectories, comparing important processes that have been conserved during the nearly 200 million years of evolution since humans and mice diverged from their common mammalian ancestor. The study details the similar genetic machinery that underpins nephron formation in humans and mice, enabling other groups of scientists to follow the logic of these developmental programs to make new types of kidney cells. from Top Health News -- ScienceDaily https://ift.tt/3AXqND4 via IFTTT

Steep rise in cardiac arrests associated with opioid use

A nationwide US study has shown that the rate of opioid-related cardiac arrests has steeply risen and is now on par with the rate of cardiac arrest from other causes. Opioid use disorder, which includes dependence and addiction, affects more than two million people in the US, while opioid overdose is the leading cause of death for those aged 25 to 64 years. This study examined the trends and outcomes of opioid-related cardiac arrest in 2012 to 2018. The US Nationwide Readmissions Database (NRD) was used to study all hospitalisations for cardiac arrest in active or chronic opioid users compared to cardiac arrests in patients not using opioids. from Top Health News -- ScienceDaily https://ift.tt/3y9uEv2 via IFTTT

Scientists distill cow’s milk into nano-capsules for drug delivery

Scientists have developed a novel way to isolate exosomes from cow's milk. Exosomes are nano-sized biological capsules that cells produce to protect and courier delicate molecules throughout the body. Harvesting them to achieve clinical-grade levels of purity, however, is a complex process. from Top Health News -- ScienceDaily https://ift.tt/3D3cL4y via IFTTT

Using artificial intelligence for early detection and treatment of illnesses

Artificial intelligence (AI) will fundamentally change medicine and healthcare: Diagnostic patient data, e.g. from ECG, EEG or X-ray images, can be analyzed with the help of machine learning, so that diseases can be detected at a very early stage based on subtle changes. However, implanting AI within the human body is still a major technical challenge. Scientists have now succeeded in developing a bio-compatible implantable AI platform that classifies in real time healthy and pathological patterns in biological signals such as heartbeats. It detects pathological changes even without medical supervision. from Top Health News -- ScienceDaily https://ift.tt/3z8qfcU via IFTTT

Distress signal from fat cells prompts heart to shore up defenses against consequences of obesity

A stress signal received by the heart from fat could help protect against cardiac damage induced by obesity, a new study suggests. The finding could help explain the 'obesity paradox,' a phenomenon in which obese individuals have better short- and medium-term cardiovascular disease prognoses compared with those who are lean, but with ultimately worse long-term outcomes. from Top Health News -- ScienceDaily https://ift.tt/3kd3XjX via IFTTT

New insights on mechanism that could help treat muscle-related diseases

Expression of the MyoD gene combined with exposure to three chemicals causes skin cells to become primitive muscle progenitors that can be maintained indefinitely in the lab and later coaxed into becoming mature muscle cells to treat muscle-related diseases. Skin-derived muscle progenitors are molecularly similar to muscle tissue stem cells, and muscle cells derived from these progenitors are more stable and mature than muscle cells directly converted from skin cells. from Top Health News -- ScienceDaily https://ift.tt/382hPbh via IFTTT

Sequential-combinatorial regimens can make treatment more effective for people with aggressive cancers

A new preclinical study suggests that treating people who have aggressive cancers, including melanoma, pancreatic and colorectal cancers, with immune checkpoint inhibitors, quickly followed with mutation-targeted therapy, can help overcome treatment resistance and help people live longer. from Top Health News -- ScienceDaily https://ift.tt/2WbLfkC via IFTTT

Cardiovascular disorder genetic testing in children presents unique challenges

Genetic testing for cardiovascular disorders is rapidly expanding, including among children. In its first scientific statement focused on the issue of cardiovascular genetic testing specifically among children, the American Heart Association provides information and guidance on the topic, including issues of timing, consent, family counseling before and after testing, and follow-up. from Top Health News -- ScienceDaily https://ift.tt/3BcVoNd via IFTTT

Superconducting nanowire single-photon detectors: Next big thing in blood flow measurement

Diffuse correlation spectroscopy (DCS) is used for noninvasive detection of blood flow. However, current DCS devices need to be improved to increase the signal-to-noise ratio for more accurate measurements. Now, researchers have developed a superconducting nanowire single-photon detector (SNSPD) -- based DCS device with a high signal-to-noise ratio and high sensitivity for blood flow. from Top Health News -- ScienceDaily https://ift.tt/3sBDjF7 via IFTTT

How ions get their electrons back

Very unusual atomic states are produced at TU Wien: Ions are created by removing not just one but 20 to 40 electrons from each atom. These "highly charged ions" play an important role in current research. For a long time, people have been investigating what happens when such highly charged ions hit solid materials. This is important for many areas of application in materials research. Therefore it is crucial to know how the charge state of the ions change when they penetrate a material -- but this is exactly what has been impossible to observe directly until now. New measurements at TU Wien (Vienna) show that the ions obey remarkably simple laws. from Top Health News -- ScienceDaily https://ift.tt/3mrnksa via IFTTT

New study sheds light on how an autoimmune disorder may underlie male infertility

Investigators have found that the absence of autoimmune regulator (Aire) in mice results in fertility problems similar to those affecting men with autoimmune polyendocrine syndrome type I (APS-1). Aire-dependent central tolerance plays a critical role in maintaining male fertility by preventing autoimmune attack against multiple reproductive targets, they report. from Top Health News -- ScienceDaily https://ift.tt/3y3rFUW via IFTTT

Study shows uptick in U.S. alcohol beverage sales during COVID-19 pandemic

During the COVID-19 pandemic months of March 2020 to September 2020, U.S. alcohol retail store sales increased compared to usual trends while food services and drinking places sales decreased markedly during the same period, according to a new study. These results indicate an increase in home drinking in the U.S. from Top Health News -- ScienceDaily https://ift.tt/3B1dDVo via IFTTT

A master gear in the circadian clock

A gene called Npas4, already known to play a key role in balancing excitatory and inhibitory inputs in brain cells, appears to also be a master timekeeper for the brain's circadian clock, new research suggests. The finding broadens understanding of the circadian clock's molecular mechanisms, which could eventually lead to new treatments for managing challenges such as jet lag, shift work, and sleep disorders. from Top Health News -- ScienceDaily https://ift.tt/3B2QL8h via IFTTT

Study could offer hope to Pompe disease patients

Pompe disease is a rare genetic disorder that disables heart and skeletal muscles and can lead to early death if untreated. The only available treatment for the disease is enzyme replacement therapy that must be injected regularly, sometimes every few days, for life. The treatment can cost hundreds of thousands of dollars a year. Researchers have now developed a method that could make enzyme replacement therapy more efficient, less expensive and less frequent. from Top Health News -- ScienceDaily https://ift.tt/2W4Dwoh via IFTTT

You’re cooler than you think! Hypothermia may go unnoticed when exercising in the cold

An exercise physiology study has demonstrated that perception of core body temperature is altered by low-intensity exercise in cold environments. The findings have provided important information about the role of temperature sensation in thermoregulation and suggest that, during activities performed in the water or in the winter, the possibility of accidental hypothermia should be kept in mind. from Top Health News -- ScienceDaily https://ift.tt/2WaRJjY via IFTTT

New approach identifies T cells in COVID-19 patients

T cells play a decisive role in fighting the coronavirus and preventing infected individuals from becoming seriously ill. They identify and fight the virus directly within the infected cells. Researchers have produced a precise profile of the T cells that respond to SARS-CoV-2 and described them at various stages of the illness. This novel methodological approach may in the future also help to assess the efficacy of SARS-CoV-2 vaccines or in the development of T cell-based treatments for serious cases. from Top Health News -- ScienceDaily https://ift.tt/3B12Fzc via IFTTT

Researchers develop steerable catheter for brain surgery

A team of engineers and physicians has developed a steerable catheter that will give neurosurgeons the ability to steer the device in any direction they want while navigating the brain's arteries and blood vessels. The device was inspired by nature, specifically insect legs and flagella -- tail-like structures that allow microscopic organisms such as bacteria to swim. from Top Health News -- ScienceDaily https://ift.tt/3gjv5ge via IFTTT

Teens who use cannabis frequently more likely to have premature baby

Teenagers who use cannabis frequently may be more likely to have children born preterm, when they become parents up to twenty years later, finds a new study. The research repeatedly assessed 665 participants in a general population cohort on their tobacco and cannabis use between ages 14 to 29 years, before pregnancy. from Top Health News -- ScienceDaily https://ift.tt/3AV8luD via IFTTT

Too much time on a computer, watching TV or other sedentary activities raises stroke risk

Adults younger than age 60 who spent eight or more hours a day during their free time using a computer, watching TV or reading and participated in little physical activity had an increased risk of stroke. Boosting physical activity may reduce or eliminate the increased stroke risk from prolonged sedentary time. Public health efforts to increase physical activity and reduce sedentary time in adults younger than age 60 could help to lower their long-term stroke risk. from Top Health News -- ScienceDaily https://ift.tt/3AVROqp via IFTTT

Experts urge caution, increased education about opioid use for people with heart disease

Opioid overdose is a leading cause of injury-related death for adults ages 25 to 54 in the U.S. Recent data suggest that commonly used opioids for pain management may interfere with medications used to manage and treat cardiovascular disease and stroke. from Top Health News -- ScienceDaily https://ift.tt/3sE3ivW via IFTTT

No significant benefit of convalescent plasma for COVID-19 outpatients with early symptoms, study shows

The final results of the Clinical Trial of COVID-19 Convalescent Plasma in Outpatients (C3PO) demonstrate that COVID-19 convalescent plasma did not prevent disease progression in a high-risk group of outpatients with COVID-19, when administered within the first week of their symptoms. The trial was stopped in February 2021 due to lack of efficacy based on a planned interim analysis. from Top Health News -- ScienceDaily https://ift.tt/37Tv5ip via IFTTT

Researchers bioprint an entire active glioblastoma tumor using a 3D printer

The 3D print of glioblastoma -- the deadliest type of brain cancer -- is printed from human glioblastoma tissues containing all components of the malignant tumor. Researchers say the breakthrough will enable much faster prediction of best treatments for patients, accelerate the development of new drugs and discovery of new druggable targets. from Top Health News -- ScienceDaily https://ift.tt/3kc4d2V via IFTTT

How fructose in the diet contributes to obesity

Eating fructose appears to alter cells in the digestive tract in a way that enables it to take in more nutrients, according to a preclinical study. These changes could help to explain the well-known link between rising fructose consumption around the world and increased rates of obesity and certain cancers. from Top Health News -- ScienceDaily https://ift.tt/3AMeNEm via IFTTT

Attractiveness pays off at work — but there’s a trick to level the playing field

A new study found that while a 'beauty premium' exists across professions, it's partially because attractive people develop distinct traits as a result of how the world responds to their attractiveness. They build a greater sense of power and have more opportunities to improve nonverbal communication skills throughout their lives. from Top Health News -- ScienceDaily https://ift.tt/37U5cPx via IFTTT

Key mechanisms behind synapse degeneration in Alzheimer’s brain discovered

Neurobiologists have uncovered the long-sought-after mechanisms behind the maintenance and decline of key synapses implicated in brain disorders such as Alzheimer's disease. The researchers identified the main components driving amyloid beta-associated synapse degeneration, which is found in the brains of people with Alzheimer's. The findings suggest an alternative approach to addressing neurodegenerative disorders: protect synapses by directly blocking the toxic actions of amyloid beta. from Top Health News -- ScienceDaily https://ift.tt/3iYotFB via IFTTT

Magnets could offer better control of prosthetic limbs

Researchers have developed a new strategy that could offer much more precise control of prosthetic limbs. After inserting small magnetic beads into muscle tissue, they can accurately measure the length of a muscle as it contracts, and this measurement can be relayed to a robotic prosthesis within milliseconds. from Top Health News -- ScienceDaily https://ift.tt/3CZXgdF via IFTTT

From mathematics to medicine: Applying complex mathematics to analyze fMRI data

Mathematical research is aiding in the analysis of fMRI data. fMRI is the preeminent class of signals collected from the brain in vivo and is irreplaceable in the study of brain dysfunction in many medical fields, including psychiatry, neurology and pediatrics. from Top Health News -- ScienceDaily https://ift.tt/3k8iXzA via IFTTT

Cancer therapy breakthrough in vitro using self-assembled drugs

A team of scientists has discovered chemical systems that self-assemble into molecular capsules which are highly toxic towards human cancer cells of a range of different tumor types, and which have demonstrated unprecedented cancer selectivity in the laboratory that in some cases are many thousands of times more toxic to the cancer cells compared to healthy, normal cells. from Top Health News -- ScienceDaily https://ift.tt/3sC3f3K via IFTTT

Previously unrecognized genetic mutation may underlie some cases of sudden infant death

A previously healthy infant who suffered aborted sudden cardiac death was found to have a de novo genetic mutation in the SOS1 gene. Such mutations are typical of Noonan syndrome and suggests the syndrome may be a cause of unrecognized sudden death in infancy. from Top Health News -- ScienceDaily https://ift.tt/3ghjFcH via IFTTT

Wash your hands for 20 seconds: Physics shows why

Researchers describe a simple model that captures the key mechanics of hand-washing, estimating the time scales on which particles, like viruses and bacteria, were removed. Particles are trapped on the rough surfaces of the hand in potential wells, as though they are at the bottom of a valley and the energy from the water flow must be high enough to get them up and out of the valley. from Top Health News -- ScienceDaily https://ift.tt/37TFU3I via IFTTT

Cooperation under pressure: Lessons from the COVID-19 swab crisis

A major crisis that accompanied the rise of the pandemic was lack of availability of the nasopharyngeal swab -- necessary for testing for COVID-19, which in turn, was necessary to get a grip on the pandemic. An account of how one group addressed that crisis is published this week Journal of Clinical Microbiology, a journal of the American Society for Microbiology. from Top Health News -- ScienceDaily https://ift.tt/3ges0Og via IFTTT

Tailoring wearable technology and telehealth in treating Parkinson's disease

Wearable health technologies are vastly popular with people wanting to improve their physical and mental health. Everything from exercise, sleep patterns, calories consumed and heart rhythms can be tracked by a wearable device. But timely and accurate data is also especially valuable for doctors treating patients with complicated health conditions using virtual care. from Top Health News -- ScienceDaily https://ift.tt/2Xy7t0B via IFTTT

Does Alzheimer’s disease start inside nerve cells?

An experimental study has revealed that the Alzheimer's protein amyloid-beta accumulates inside nerve cells, and that the misfolded protein may then spread from cell to cell via nerve fibers. This happens at an earlier stage than the formation of amyloid-beta plaques in the brain, something that is associated with the progression of Alzheimer's disease. from Top Health News -- ScienceDaily https://ift.tt/37VwAMY via IFTTT

Progress continues in ensuring safety for nation’s high school athletes

Researchers began publishing annual reports and bi-annual updates examining the health and safety policies for secondary schools for each individual state and Washington, D.C. The evaluations are based on safety measures states can implement, including emergency action plans, having automatic external defibrillators on site, training coaches to look for signs of concussion, treatment of exertional heat stroke and others. from Top Health News -- ScienceDaily https://ift.tt/3yYyM20 via IFTTT

Inhibitor drug entinostat ‘primes’ the body to better respond to anti-cancer treatment with immunotherapy

Combining a histone deacetylase inhibitor drug with immunotherapy agents has been deemed safe, and may benefit some patients with advanced cancers that have not responded to traditional therapy, according to results of a phase 1 clinical trial. from Top Health News -- ScienceDaily https://ift.tt/3geELbz via IFTTT

How a Parkinson’s disease-linked protein attacks a cell’s powerhouses

Inside cells, organelles called mitochondria carry out a medley of vital tasks. These structures generate energy and help to keep the cells' interior environment in a state of healthy equilibrium, among other functions. Now, scientists show in detail how alpha-synuclein, a protein associated with Parkinson's disease, can damage these cellular powerhouses. from Top Health News -- ScienceDaily https://ift.tt/3iXDR5l via IFTTT

Sounds and words are processed separately and simultaneously in the brain

After years of research, neuroscientists have discovered a new pathway in the human brain that processes the sounds of language. The findings suggest that auditory and speech processing occur in parallel, contradicting a long-held theory that the brain processed acoustic information then transformed it into linguistic information. from Top Health News -- ScienceDaily https://ift.tt/3zbu0hC via IFTTT

Genetic histories and social organization in Neolithic and Bronze Age Croatia

The field of Archaeogenetics has substantially contributed to a better understanding of how the movement and admixture of people across Europe during the Neolithic and Bronze Ages shaped genetic ancestries. However, not all regions are equally well represented in the archaeogenetic record. To fill this gap, researchers have now sequenced whole genomes of 28 individuals from two sites in present-day eastern Croatia and gained new insights into this region's genetic history and social structures. from Top Health News -- ScienceDaily https://ift.tt/3yZNBBA via IFTTT

Obstructive sleep apnea is common in kids and may impact blood pressure, heart health

Children and adolescents can experience sleep-disordered breathing and obstructive sleep apnea, like adults. An estimated 1-6% of all children and adolescents have obstructive sleep apnea. The sleep disruptions and pauses in breathing from sleep apnea may be linked to obesity, lipid disorders, elevated blood pressure and changes in heart structure in kids. from Top Health News -- ScienceDaily https://ift.tt/3iWPLfJ via IFTTT

COVID-19 pandemic linked to an increase in intimate partner aggression, study shows

Rates of physical and psychological aggression among couples increased significantly after the implementation of shelter-in-place restrictions at the outset of the COVID-19 pandemic, according to a new study. The findings indicate that stress related to the pandemic was strongly associated with perpetration of intimate partner aggression, even among individuals considered at low risk. from Top Health News -- ScienceDaily https://ift.tt/3iTBHmV via IFTTT

Vaccine stockpiling by nations could lead to increase in COVID-19 cases, novel variant emergence, study finds

The extent of vaccine nationalism, wherein countries stockpile vaccines to prioritize access for their citizenry over equitable vaccine sharing, may strongly impact global trajectories of COVID-19 case numbers and increase the potential emergence of novel variants, according to a new study. from Top Health News -- ScienceDaily https://ift.tt/3yRyGt3 via IFTTT

Use your team’s emotions to boost creativity

If you're putting together a team for a project, you might be inclined to pick people with cheerful, optimistic dispositions and flexible thinking. But a new management study indicates your team might also benefit from people who are exactly the opposite. from Top Health News -- ScienceDaily https://ift.tt/3AOMlSf via IFTTT

Antibodies elicited by COVID-19 vaccination effective against delta variant

Researchers have found that the delta variant of the virus that causes COVID-19 is largely unable to evade antibodies elicited by vaccination. The findings help explain why vaccinated people have been at low risk of getting seriously ill with COVID-19 despite a surge in cases caused by the delta variant. from Top Health News -- ScienceDaily https://ift.tt/3iR0eJw via IFTTT

Dieting: Villain or scapegoat?

For decades, there has been an accepted definition of dieting in academia, and in society as a whole. Researchers recently reevaluated the decades of dieting research to redefine the way researchers and the public define -- and therefore understand - dieting and the culture of weight loss. from Top Health News -- ScienceDaily https://ift.tt/3gbWhgK via IFTTT

How microbes can exacerbate cognitive decline

Recent research has found that changes in the gut microbiota -- the trillions of bacteria and other microbes that live in the intestines -- can alter the brain and behavior. A new study could elucidate how and why that phenomenon occurs. from Top Health News -- ScienceDaily https://ift.tt/3mcxBs7 via IFTTT

Genome-editing strategy developed for potential Alzheimer’s disease therapy

Scientists have developed a novel strategy using brain-wide genome-editing technology that can reduce Alzheimer's disease(AD) pathologies in genetically modified AD mouse models. This advanced technology offers immense potential to be translated as a novel long-acting therapeutic treatment for AD patients. from Top Health News -- ScienceDaily https://ift.tt/3xPnWdm via IFTTT

Benefits of time-restricted eating depend on age and sex

Time-restricted eating (TRE), a dietary regimen that restricts eating to specific hours, has garnered increased attention in weight-loss circles. A new study further shows that TRE confers multiple health benefits besides weight loss. The study also shows that these benefits may depend on sex and age. from Top Health News -- ScienceDaily https://ift.tt/3ss5sOR via IFTTT

Gender revolutions in who holds the purse strings

New research has uncovered considerable class differences in the gender revolution of who holds the purse strings among British couples. Low-earning and high-earning women are taking more control of the finances in their relationships, but in different ways, says the research. from Top Health News -- ScienceDaily https://ift.tt/3m7e0tD via IFTTT

Brain organoids develop optic cups that respond to light

Human induced pluripotent stem cells (iPSCs) can be used to generate brain organoids containing an eye structure called the optic cup, according to a new study. The organoids spontaneously developed bilaterally symmetric optic cups from the front of the brain-like region, demonstrating the intrinsic self-patterning ability of iPSCs in a highly complex biological process. from Top Health News -- ScienceDaily https://ift.tt/3CNB1HM via IFTTT

Hamster study evaluates airborne and fomite transmission of SARS-CoV-2

Scientists studying SARS-CoV-2, the virus that causes COVID-19, have defined in Syrian hamsters how different routes of virus exposure are linked to disease severity. Their study details the efficiency of airborne transmission between hamsters and examines how the virus replicates and causes disease throughout the respiratory system. from Top Health News -- ScienceDaily https://ift.tt/3iPSE1M via IFTTT

Researchers confirm speed, simplicity and sensitivity for new COVID-19 test

Researchers have published a three way comparison study to confirm that the Reverse Transcriptase Free Exponential Amplification Reaction (RTF-EXPAR) method is just as sensitive, but faster, than both PCR and LAMP tests. The study revealed that the RTF-EXPAR method converts under 10 strands of RNA into billions of copies of DNA in under 10 minutes, using a one-pot assay that is compatible with more basic, benchtop equipment than that used with current testing methods. from Top Health News -- ScienceDaily https://ift.tt/2XE3DU1 via IFTTT

Researchers uncover evolutionary forces at play in the aging of the blood system and identify people at increased risk of blood cancer

Study shows how the interplay of positive, neutral and negative evolutionary selection acting on mutations in aging blood stem cells can lead to acute myeloid leukemia (AML) in some individuals with age-related clonal hematopoiesis (ARCH). from Top Health News -- ScienceDaily https://ift.tt/3CNcP8q via IFTTT

New research provides clues to developing better intranasal vaccines for COVID-19 and flu

While gut microbiota play a critical role in the induction of adaptive immune responses to influenza virus infection, the role of nasal bacteria in the induction of virus-specific adaptive immunity is less clear. New research explores the role of nasal bacteria and provides clues to developing better intranasal vaccines for flu and COVID-19. from Top Health News -- ScienceDaily https://ift.tt/3CUlWnL via IFTTT

Mutated enzyme weakens connection between brain cells that help control movement

In one type of a rare, inherited genetic disorder that affects control of body movement, scientists have found a mutation in an enzyme impairs communication between neurons and what should be the inherent ability to pick up our pace when we need to run, instead of walk, across the street. from Top Health News -- ScienceDaily https://ift.tt/3g5AuY7 via IFTTT

Small protein protects pancreatic cells in model of type 1 diabetes

A new study has shown that treating type 1 diabetes-prone mice with the small protein MOTS-c prevented the immune system from destroying insulin-producing pancreatic cells, effectively preventing the onset of the autoimmune disease. The small protein that first made headlines as an 'exercise mimetic' increasingly appears to also have a big role in regulating the immune system. from Top Health News -- ScienceDaily https://ift.tt/2XtQUCZ via IFTTT

Blind people can’t see color but understand it the same way as sighted people

People born blind have never seen that bananas are yellow but researchers find that like any sighted person, they understand two bananas are likely to be the same color and why. Questioning the belief that dates back to philosopher John Locke that people born blind could never truly understand color, the team of cognitive neuroscientists demonstrated that congenitally blind and sighted individuals actually understand it quite similarly. from Top Health News -- ScienceDaily https://ift.tt/3jYKnrL via IFTTT

Experimental drug that boosts immunotherapy shows promise in bladder cancer study

Researchers have found adding the experimental drug entinostat to an immunotherapy-like treatment substantially boosted cancer remission in mice. This approach shows such promise that it's already being tested in an ongoing clinical trial in people with advanced bladder cancer. from Top Health News -- ScienceDaily https://ift.tt/37QSjFP via IFTTT

Scientists develop faster COVID-19 test

Scientists have developed a new sample preparation method to detect SARS-CoV-2, the virus that causes COVID-19. The method bypasses extraction of the virus' genetic RNA material, simplifying sample purification and potentially reducing test time and cost. from Top Health News -- ScienceDaily https://ift.tt/3sm7eB7 via IFTTT

Night shift work is linked to increased risk of heart problems

Using data from over 283,600 people in UK Biobank, researchers have found that people who work night shifts are at increased risk of developing an irregular and often abnormally fast heart rhythm called atrial fibrillation, and they are also at an increased risk of heart disease. Women and people who don't exercise regularly are most at risk. from Top Health News -- ScienceDaily https://ift.tt/3g3Toyj via IFTTT

Less passive screen time, more structure better for kids' mental health during pandemic

There are a number of simple, practical steps that families can take -- including reducing passive screen time and news consumption, having a structured daily schedule and getting enough sleep -- that can promote resilience against mental health problems in youth during the COVID-19 pandemic, according to a new study. from Top Health News -- ScienceDaily https://ift.tt/3iQb8PF via IFTTT

Survivors of trauma struggle to move on from the loss of loved ones

Among individuals who survive a trauma that resulted in the loss of a close friend or loved one, symptoms of post-traumatic stress disorder can predict complicated grief -- a sense of persistent sadness and an inability to cope -- years after the trauma, according to new research. from Top Health News -- ScienceDaily https://ift.tt/3m8WPYy via IFTTT