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Early warning signals could help monitor disease outbreaks

New research suggests early warning signals (EWSs) could help in the monitoring of disease outbreaks, such as COVID-19. The study found warnings could be detected weeks earlier than any rapid increase in cases. The findings could help governments and policy makers improve the accuracy of their decisions and allow timely interventions if needed. from Top Health News -- ScienceDaily https://ift.tt/3DvxDk4 via IFTTT
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Researchers discover how cellular senescence leads to neurodegeneration

Although a link has been established between chronic inflammation and neurodegenerative diseases, there have been many open questions regarding how cellular senescence, a process whereby cells that stop dividing under stress spew out a mix of inflammatory proteins, affects these pathologies. Researchers report that senescence in astrocytes, the most abundant cell type in the brain, leads to damaging ''excitotoxicity'' in cortical neurons that are involved in memory.

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Pathomechanisms in heart disease discovered

The largest protein in the human body, titin, enables elastic movements of our muscles, including the heart. Mutations in the titin gene (TTN) that impair this function and lead to heart muscle disease. The pathomechanisms behind this -- i.e. why TTN mutations trigger disease -- were unclear until now. A team of experts has now investigated these pathomechanisms in more detail and has gained ground-breaking insights. from Top Health News -- ScienceDaily https://ift.tt/3EOEi9S via IFTTT
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