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The circadian clock system allows the organisms to adjust to periodical changes of geophysical time. Today, increasing evidence show that disturbances in our internal clocks stemming from frequent time zone changes, irregular working schedules or ageing, have a significant impact on the development of metabolic diseases including type-2 diabetes. Using a molecule extracted from lemon peel, researchers have succeeded in 'repairing' the disrupted cellular clocks. from Top Health News -- ScienceDaily https://ift.tt/38SCiO7 via IFTTT

Thanks to new research, a drug capable of reversing a common form of heart failure known as heart failure with preserved ejection fraction (HFpEF) may soon be available. The researchers show that a drug already approved for the treatment of some forms of cancer can reverse HFpEF symptoms and improve the heart's ability to pump blood in an HFpEF animal model. from Top Health News -- ScienceDaily https://ift.tt/3aZL5Q3 via IFTTT

The lens of the human eye comprises a highly concentrated protein solution, which lends the lens its great refractive power. Protective proteins prevent these proteins from clumping together throughout a lifetime. A team of scientists has now uncovered the precise structure of the alpha-A-crystallin protein and, in the process, discovered an important additional function. from Top Health News -- ScienceDaily https://ift.tt/3aVpyIt via IFTTT

The lens of the human eye comprises a highly concentrated protein solution, which lends the lens its great refractive power. Protective proteins prevent these proteins from clumping together throughout a lifetime. A team of scientists has now uncovered the precise structure of the alpha-A-crystallin protein and, in the process, discovered an important additional function. from Top Health News -- ScienceDaily https://ift.tt/3aVpyIt via IFTTT

Researchers have shown that cannabidiol (CBD) alters the brain activity in people with psychosis during memory tasks, making it more similar to the activation seen in people without psychosis during the same tasks. from Top Health News -- ScienceDaily https://ift.tt/2SjxMSf via IFTTT

People who cycle to work have a lower risk of dying, a New Zealand study has found. from Top Health News -- ScienceDaily https://ift.tt/36MBXec via IFTTT

Researchers have shown that cannabidiol (CBD) alters the brain activity in people with psychosis during memory tasks, making it more similar to the activation seen in people without psychosis during the same tasks. from Top Health News -- ScienceDaily https://ift.tt/2SjxMSf via IFTTT

People who cycle to work have a lower risk of dying, a New Zealand study has found. from Top Health News -- ScienceDaily https://ift.tt/36MBXec via IFTTT

As tumors develop, cancer cells gain and lose so-called 'chromosome arms', changing their response to drugs, a finding which may offer better personalized treatments for 17 types of cancer. from Top Health News -- ScienceDaily https://ift.tt/2uPaZ8I via IFTTT

Colorectal cancer, one of the most common cancers in the developed world, is intrinsically resistant to many drug therapies. In an attempt to identify novel treatment strategies, researchers examined the contribution of serine racemase (SRR) to colorectal cancer metabolism. The researchers showed that SRR is required for cancer cell proliferation, and that inhibition of SRR in mice halted tumor progression, paving the way for future drug development. from Top Health News -- ScienceDaily https://ift.tt/3b2kiT9 via IFTTT

As tumors develop, cancer cells gain and lose so-called 'chromosome arms', changing their response to drugs, a finding which may offer better personalized treatments for 17 types of cancer. from Top Health News -- ScienceDaily https://ift.tt/2uPaZ8I via IFTTT

Colorectal cancer, one of the most common cancers in the developed world, is intrinsically resistant to many drug therapies. In an attempt to identify novel treatment strategies, researchers examined the contribution of serine racemase (SRR) to colorectal cancer metabolism. The researchers showed that SRR is required for cancer cell proliferation, and that inhibition of SRR in mice halted tumor progression, paving the way for future drug development. from Top Health News -- ScienceDaily https://ift.tt/3b2kiT9 via IFTTT

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Hokkaido University scientists are getting closer to understanding how a rare hereditary disease impairs the skin's barrier function, which determines how well the skin is protected. from Top Health News -- ScienceDaily https://ift.tt/38ScQIr via IFTTT

A new study on meta reinforcement learning algorithms helps us understand how the human brain learns to adapt to complexity and uncertainty when learning and making decisions. A research team succeeded in discovering both a computational and neural mechanism for human meta reinforcement learning, opening up the possibility of porting key elements of human intelligence into artificial intelligence algorithms. This study provides a glimpse into how it might ultimately use computational models to reverse engineer human reinforcement learning. from Top Health News -- ScienceDaily https://ift.tt/37Lp45q via IFTTT

Hokkaido University scientists are getting closer to understanding how a rare hereditary disease impairs the skin's barrier function, which determines how well the skin is protected. from Top Health News -- ScienceDaily https://ift.tt/38ScQIr via IFTTT

A new study on meta reinforcement learning algorithms helps us understand how the human brain learns to adapt to complexity and uncertainty when learning and making decisions. A research team succeeded in discovering both a computational and neural mechanism for human meta reinforcement learning, opening up the possibility of porting key elements of human intelligence into artificial intelligence algorithms. This study provides a glimpse into how it might ultimately use computational models to reverse engineer human reinforcement learning. from Top Health News -- ScienceDaily https://ift.tt/37Lp45q via IFTTT

For hundreds of years, practitioners of traditional Chinese medicine have used an herb called Stemona sessilifolia as a remedy for parasitic infections, such as those caused by pinworms and lice. Now, researchers have identified 10 compounds that might be responsible for the herb's effectiveness. But there's a twist: The insecticides are produced by symbiotic microbes that live within the plant's cells -- not by S. sessilifolia itself. from Top Health News -- ScienceDaily https://ift.tt/2UaA9ZS via IFTTT

In addition to harmful gases such as carbon monoxide, air pollution contains tiny particles that have been linked to health problems, including cardiovascular disease and asthma. from Top Health News -- ScienceDaily https://ift.tt/2GBr30n via IFTTT

Antibiotic resistance is one of the biggest threats to global health. Sensing and treating bacterial infections earlier could help improve patients' recovery, as well curb the spread of antibiotic-resistant microbes. Now, researchers have developed color-changing bandages that can sense drug-resistant and drug-sensitive bacteria in wounds and treat them accordingly. from Top Health News -- ScienceDaily https://ift.tt/37Gz2VU via IFTTT

A new study could be particularly important for those working in rehabilitation and helping people to recover after neurological conditions. from Top Health News -- ScienceDaily https://ift.tt/37Htx9t via IFTTT

WSU study finds that environmental transmission rather than antibiotic use explains the presence of antibiotic-resistant bacteria in people, domestic animals and wildlife. from Top Health News -- ScienceDaily https://ift.tt/38POHlH via IFTTT

People may lie to appear honest if events that turned out in their favor seem too good to be true, according to new research. from Top Health News -- ScienceDaily https://ift.tt/2RF2RAB via IFTTT

For hundreds of years, practitioners of traditional Chinese medicine have used an herb called Stemona sessilifolia as a remedy for parasitic infections, such as those caused by pinworms and lice. Now, researchers have identified 10 compounds that might be responsible for the herb's effectiveness. But there's a twist: The insecticides are produced by symbiotic microbes that live within the plant's cells -- not by S. sessilifolia itself. from Top Health News -- ScienceDaily https://ift.tt/2UaA9ZS via IFTTT

In addition to harmful gases such as carbon monoxide, air pollution contains tiny particles that have been linked to health problems, including cardiovascular disease and asthma. from Top Health News -- ScienceDaily https://ift.tt/2GBr30n via IFTTT

Antibiotic resistance is one of the biggest threats to global health. Sensing and treating bacterial infections earlier could help improve patients' recovery, as well curb the spread of antibiotic-resistant microbes. Now, researchers have developed color-changing bandages that can sense drug-resistant and drug-sensitive bacteria in wounds and treat them accordingly. from Top Health News -- ScienceDaily https://ift.tt/37Gz2VU via IFTTT

Researchers discovered consuming low-calorie sweeteners like aspartame and stevia while pregnant increased body fat in their offspring and disrupted their gut microbiota. from Top Health News -- ScienceDaily https://ift.tt/2GDXyuV via IFTTT

Researchers discovered consuming low-calorie sweeteners like aspartame and stevia while pregnant increased body fat in their offspring and disrupted their gut microbiota. from Top Health News -- ScienceDaily https://ift.tt/2GDXyuV via IFTTT

Researchers have discovered that a used cigarette butt - even one that is cold to the touch - can give off the equivalent of 14% of the nicotine that an actively burning cigarette emits. They are calling this newly discovered form of cigarette exposure ''after smoke'' or butt emissions. from Top Health News -- ScienceDaily https://ift.tt/36CvgeU via IFTTT

Researchers have discovered that a used cigarette butt - even one that is cold to the touch - can give off the equivalent of 14% of the nicotine that an actively burning cigarette emits. They are calling this newly discovered form of cigarette exposure ''after smoke'' or butt emissions. from Top Health News -- ScienceDaily https://ift.tt/36CvgeU via IFTTT

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Although a link has been established between chronic inflammation and neurodegenerative diseases, there have been many open questions regarding how cellular senescence, a process whereby cells that stop dividing under stress spew out a mix of inflammatory proteins, affects these pathologies. Researchers report that senescence in astrocytes, the most abundant cell type in the brain, leads to damaging ''excitotoxicity'' in cortical neurons that are involved in memory. from Top Health News -- ScienceDaily https://ift.tt/36IBSIN via IFTTT

A new study has revealed how the gut's protective mechanisms ramp up significantly with food intake, and at times of the day when mealtimes are anticipated based on regular eating habits. Researchers found that eating causes a hormone called VIP to kickstart the activity of immune cells in response to potentially incoming pathogens or 'bad' bacteria. The researchers also found that immunity increased at anticipated mealtimes indicating that maintaining regular eating patterns could be more important than previously thought. from Top Health News -- ScienceDaily https://ift.tt/36EQaKm via IFTTT

Although a link has been established between chronic inflammation and neurodegenerative diseases, there have been many open questions regarding how cellular senescence, a process whereby cells that stop dividing under stress spew out a mix of inflammatory proteins, affects these pathologies. Researchers report that senescence in astrocytes, the most abundant cell type in the brain, leads to damaging ''excitotoxicity'' in cortical neurons that are involved in memory. from Top Health News -- ScienceDaily https://ift.tt/36IBSIN via IFTTT

A new study has revealed how the gut's protective mechanisms ramp up significantly with food intake, and at times of the day when mealtimes are anticipated based on regular eating habits. Researchers found that eating causes a hormone called VIP to kickstart the activity of immune cells in response to potentially incoming pathogens or 'bad' bacteria. The researchers also found that immunity increased at anticipated mealtimes indicating that maintaining regular eating patterns could be more important than previously thought. from Top Health News -- ScienceDaily https://ift.tt/36EQaKm via IFTTT

Mixing drinking water with chlorine, the United States' most common method of disinfecting drinking water, creates previously unidentified toxic byproducts. from Top Health News -- ScienceDaily https://ift.tt/2GzRGmg via IFTTT

Researchers have developed an unrivaled, fully automated robotic screening system which allows them to rapidly test the effect of drugs and other chemicals on human sperm. The researchers are working towards finding a safe and effective male contraceptive. from Top Health News -- ScienceDaily https://ift.tt/2RX8r00 via IFTTT

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British newspapers are routinely glamorizing combat by creating a moral separation between combat and non-combat injuries, according to new research. from Top Health News -- ScienceDaily https://ift.tt/37CsKGx via IFTTT

The adoption of children is a fundamental method of building families. However, adoptees may face subsequent adaptive challenges associated with family stress at the time of birth and during the adoption process. from Top Health News -- ScienceDaily https://ift.tt/36Ep9Xc via IFTTT

The new mitochondrial DNA (mtDNA) variant drastically speeds up the disease progression in a mouse model of GRACILE syndrome. This discovery provides a new tool for studies of mitochondrial diseases. from Top Health News -- ScienceDaily https://ift.tt/2RCAPpq via IFTTT

New brain networks come 'online' during adolescence, allowing teenagers to develop more complex adult social skills, but potentially putting them at increased risk of mental illness, according to new research. from Top Health News -- ScienceDaily https://ift.tt/2U4HPNm via IFTTT

Some forms of domestic violence double victims' risk of depression and anxiety disorders later in life, according to recent research. from Top Health News -- ScienceDaily https://ift.tt/2GvTvRe via IFTTT

British newspapers are routinely glamorizing combat by creating a moral separation between combat and non-combat injuries, according to new research. from Top Health News -- ScienceDaily https://ift.tt/37CsKGx via IFTTT

The adoption of children is a fundamental method of building families. However, adoptees may face subsequent adaptive challenges associated with family stress at the time of birth and during the adoption process. from Top Health News -- ScienceDaily https://ift.tt/36Ep9Xc via IFTTT

The new mitochondrial DNA (mtDNA) variant drastically speeds up the disease progression in a mouse model of GRACILE syndrome. This discovery provides a new tool for studies of mitochondrial diseases. from Top Health News -- ScienceDaily https://ift.tt/2RCAPpq via IFTTT

New brain networks come 'online' during adolescence, allowing teenagers to develop more complex adult social skills, but potentially putting them at increased risk of mental illness, according to new research. from Top Health News -- ScienceDaily https://ift.tt/2U4HPNm via IFTTT

Some forms of domestic violence double victims' risk of depression and anxiety disorders later in life, according to recent research. from Top Health News -- ScienceDaily https://ift.tt/2GvTvRe via IFTTT

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A new approach that uses artificial intelligence to analyze retinal images could one day help doctors select the best treatment for patients with vision loss from diabetic macular edema. This diabetes complication is a major cause of vision loss among working-age adults. from Top Health News -- ScienceDaily https://ift.tt/36y3f8d via IFTTT

Scientists have invented a nanoparticle that eats away -- from the inside out -- portions of plaques that cause heart attacks. from Top Health News -- ScienceDaily https://ift.tt/2GrVcPI via IFTTT

A new approach that uses artificial intelligence to analyze retinal images could one day help doctors select the best treatment for patients with vision loss from diabetic macular edema. This diabetes complication is a major cause of vision loss among working-age adults. from Top Health News -- ScienceDaily https://ift.tt/36y3f8d via IFTTT

Scientists have invented a nanoparticle that eats away -- from the inside out -- portions of plaques that cause heart attacks. from Top Health News -- ScienceDaily https://ift.tt/2GrVcPI via IFTTT

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Students' high school grade point averages are five times stronger than their ACT scores at predicting college graduation, according to a new study. from Top Health News -- ScienceDaily https://ift.tt/3161E8C via IFTTT

There is an increased risk of out-of-hospital cardiac arrest even from short-term exposure to low concentrations of dangerously small particulate matter PM2.5, an international study has found, noting an association with gaseous pollutants such as those from coal burning, wildfires/bushfires and motor vehicles. The authors call for a tightening of standards worldwide; the findings also point to the need to transition to cleaner energy. from Top Health News -- ScienceDaily https://ift.tt/2RAe8SL via IFTTT

Students' high school grade point averages are five times stronger than their ACT scores at predicting college graduation, according to a new study. from Top Health News -- ScienceDaily https://ift.tt/3161E8C via IFTTT

There is an increased risk of out-of-hospital cardiac arrest even from short-term exposure to low concentrations of dangerously small particulate matter PM2.5, an international study has found, noting an association with gaseous pollutants such as those from coal burning, wildfires/bushfires and motor vehicles. The authors call for a tightening of standards worldwide; the findings also point to the need to transition to cleaner energy. from Top Health News -- ScienceDaily https://ift.tt/2RAe8SL via IFTTT

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The controversy about whether eggs are good or bad for your heart health may be solved, and about one a day is fine. A team of researchers found the answer by analyzing data from three large, long-term multinational studies. from Top Health News -- ScienceDaily https://ift.tt/36EmSeZ via IFTTT

The controversy about whether eggs are good or bad for your heart health may be solved, and about one a day is fine. A team of researchers found the answer by analyzing data from three large, long-term multinational studies. from Top Health News -- ScienceDaily https://ift.tt/36EmSeZ via IFTTT

Eating walnuts may help slow cognitive decline in at-risk groups of the elderly population, according to a study conducted by researchers in California and Spain. from Top Health News -- ScienceDaily https://ift.tt/2O3GJgQ via IFTTT

Eating walnuts may help slow cognitive decline in at-risk groups of the elderly population, according to a study conducted by researchers in California and Spain. from Top Health News -- ScienceDaily https://ift.tt/2O3GJgQ via IFTTT

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A five-year follow-up study of more than 2,000 US men who received prostate cancer treatment is creating a road map for future patients regarding long-term bowel, bladder and sexual function in order to clarify expectations and enable men to make informed choices about care. from Top Health News -- ScienceDaily https://ift.tt/2Rzl56t via IFTTT

A five-year follow-up study of more than 2,000 US men who received prostate cancer treatment is creating a road map for future patients regarding long-term bowel, bladder and sexual function in order to clarify expectations and enable men to make informed choices about care. from Top Health News -- ScienceDaily https://ift.tt/2Rzl56t via IFTTT

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Researchers have found that 94% of middle school teachers experience high levels of stress, which could contribute to negative outcomes for students. Researchers say that reducing the burden of teaching experienced by so many teachers is critical to improve student success -- both academically and behaviorally. from Top Health News -- ScienceDaily https://ift.tt/2RV1Q69 via IFTTT

A new-method analyzes the combination of tumor genetic material (genomics) with deep protein and phosphoprotein characterization (proteomics) using a single-needle core biopsy from a patient's tumor, providing more detailed information about the cancer than conventional approaches. from Top Health News -- ScienceDaily https://ift.tt/36puXUA via IFTTT

Recreational fishers are increasingly targeting sharks and rays, a situation that is causing concern among researchers. from Top Health News -- ScienceDaily https://ift.tt/2vmx12F via IFTTT

Researchers found that not only do individual mammalian cells in a population fail to respond synchronously to estrogen stimulation, neither do individual gene copies, known as alleles. from Top Health News -- ScienceDaily https://ift.tt/38GTMNg via IFTTT

A groundbreaking tumor-highlighting technology -- OTL38 -- enhances the visualization of lung cancer tissue, providing surgeons with a significantly better chance of finding and removing more cancer than previously possible. from Top Health News -- ScienceDaily https://ift.tt/30Xmo2d via IFTTT

Men are not better than women at spatial cognition -- such as map reading -- is the principal finding from ground-breaking work. from Top Health News -- ScienceDaily https://ift.tt/38GKYXJ via IFTTT

Researchers have identified several potentially useful breast cancer biomarkers that indicate the presence and risk of malignancy, according to new research. from Top Health News -- ScienceDaily https://ift.tt/3aMKalQ via IFTTT

Scientists have devised a functioning comprehensive multi-Organ-on-a-Chip (Organ Chip) platform that enables effective preclinical drug testing of human drug pharmacology. from Top Health News -- ScienceDaily https://ift.tt/30ZGdGf via IFTTT

Researchers have found that 94% of middle school teachers experience high levels of stress, which could contribute to negative outcomes for students. Researchers say that reducing the burden of teaching experienced by so many teachers is critical to improve student success -- both academically and behaviorally. from Top Health News -- ScienceDaily https://ift.tt/2RV1Q69 via IFTTT

A new-method analyzes the combination of tumor genetic material (genomics) with deep protein and phosphoprotein characterization (proteomics) using a single-needle core biopsy from a patient's tumor, providing more detailed information about the cancer than conventional approaches. from Top Health News -- ScienceDaily https://ift.tt/36puXUA via IFTTT

Recreational fishers are increasingly targeting sharks and rays, a situation that is causing concern among researchers. from Top Health News -- ScienceDaily https://ift.tt/2vmx12F via IFTTT

Researchers found that not only do individual mammalian cells in a population fail to respond synchronously to estrogen stimulation, neither do individual gene copies, known as alleles. from Top Health News -- ScienceDaily https://ift.tt/38GTMNg via IFTTT

A groundbreaking tumor-highlighting technology -- OTL38 -- enhances the visualization of lung cancer tissue, providing surgeons with a significantly better chance of finding and removing more cancer than previously possible. from Top Health News -- ScienceDaily https://ift.tt/30Xmo2d via IFTTT

Men are not better than women at spatial cognition -- such as map reading -- is the principal finding from ground-breaking work. from Top Health News -- ScienceDaily https://ift.tt/38GKYXJ via IFTTT

Researchers have identified several potentially useful breast cancer biomarkers that indicate the presence and risk of malignancy, according to new research. from Top Health News -- ScienceDaily https://ift.tt/3aMKalQ via IFTTT

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A research team maps neural activity in response to watching horror movies. A study shows the top horror movies of the past 100 years, and how they manipulate brain activity. from Top Health News -- ScienceDaily https://ift.tt/2U0C6bg via IFTTT

Like animals and humans, plants possess a kind of immune system. It can e.g. recognize pathogenic fungi by the chitin in their cell walls, triggering disease resistance. Some fungi hide from the immune system by modifying some of the chitin building blocks, converting chitin into chitosan. Researchers now found that plants can react to a certain pattern in this chitosan, stimulating their immune system. from Top Health News -- ScienceDaily https://ift.tt/38F8Pag via IFTTT

A rare, African-specific variant of the TP53 gene called P47S causes iron accumulation in macrophages and other cell types and is associated with poorer response to bacterial infections, along with markers of iron overload in African Americans. Macrophage iron accumulation disrupts their function, resulting in more severe bacterial infections. from Top Health News -- ScienceDaily https://ift.tt/2TY2cMc via IFTTT

Identification of a protein complex that attracts or repels nerve cells during development. from Top Health News -- ScienceDaily https://ift.tt/2RtT9kA via IFTTT

To mitigate climate change and safeguard ecosystems, we need to make drastic changes in our consumption and transport behaviors. A new study shows how even minor changes to available infrastructure can trigger tipping points in the collective adoption of sustainable behaviors. from Top Health News -- ScienceDaily https://ift.tt/37uKvrw via IFTTT

Researchers found that myelin, the sheath around neurons, creates a coaxial cable producing multiple waves of electrical potentials traveling in a more complicated manner than was envisioned earlier. These findings allow us to create better theories and tools to understand demyelinating diseases, including the most common neurological disorder, multiple sclerosis. from Top Health News -- ScienceDaily https://ift.tt/2GqbN6A via IFTTT

A research team maps neural activity in response to watching horror movies. A study shows the top horror movies of the past 100 years, and how they manipulate brain activity. from Top Health News -- ScienceDaily https://ift.tt/2U0C6bg via IFTTT

Like animals and humans, plants possess a kind of immune system. It can e.g. recognize pathogenic fungi by the chitin in their cell walls, triggering disease resistance. Some fungi hide from the immune system by modifying some of the chitin building blocks, converting chitin into chitosan. Researchers now found that plants can react to a certain pattern in this chitosan, stimulating their immune system. from Top Health News -- ScienceDaily https://ift.tt/38F8Pag via IFTTT