Health world

Scientists have identified a natural barrier to the regeneration of the inner ear's sensory cells, which are lost in hearing and balance disorders. Overcoming this barrier may be a first step in returning inner ear cells to a newborn-like state that's primed for regeneration, as described in a new study. The study suggests new gene engineering approaches that could be used to channel some of the same regenerative capability present in embryonic inner ear cells. from Top Health News -- ScienceDaily https://ift.tt/3zViGqa via IFTTT

Researchers have shown that a targeted therapy using non-thermal radio waves is safe to use in the treatment of hepatocellular carcinoma (HCC), the most common type of liver cancer, according to a new study. The therapy also showed a benefit in overall survival. from Top Health News -- ScienceDaily https://ift.tt/2V4fvgQ via IFTTT

In the biomaterials industry, electrospinning is a ubiquitous fabrication method used to produce nano- to microscale fibrous meshes that closely resemble native tissue architecture. Alas, the process has traditionally used solvents that not only are environmentally hazardous but also a significant barrier to industrial scale-up, clinical translation, and widespread use. But now, researchers report that they have developed a 'green electrospinning' process that addresses those challenges, from managing environmental risks of volatile solvent storage and disposal at large volumes to meeting health and safety standards during both fabrication and implementation. from Top Health News -- ScienceDaily https://ift.tt/2TK7w85 via IFTTT

Symptoms for early COVID-19 infection differ among age groups and between men and women, new research has found. from Top Health News -- ScienceDaily https://ift.tt/3iZ6kGA via IFTTT

The mutations that give rise to melanoma result from a chemical conversion in DNA fueled by sunlight -- not just a DNA copying error as previously believed, reports a new study. The findings upend long-held beliefs about the mechanisms underlying the disease, reinforce the importance of prevention efforts and offer a path forward for investigating the origins of other cancer types. from Top Health News -- ScienceDaily https://ift.tt/3C8FIfd via IFTTT

Medical researchers have discovered what appears to be an Achilles' heel in ovarian cancers, as well as new biomarkers that could point to which patients are the best candidates for possible new treatments. from Top Health News -- ScienceDaily https://ift.tt/37bJxC0 via IFTTT

Researchers have found a new approach to incorporating the larger web of relevant data for predictive modeling for individual and community health outcomes. from Top Health News -- ScienceDaily https://ift.tt/2WsBXk7 via IFTTT

Researchers have found evidence that World Trade Center responders had a higher likelihood of developing liver disease if they arrived at the site right after the attacks as opposed to working at Ground Zero later in the rescue and recovery efforts. from Top Health News -- ScienceDaily https://ift.tt/2TILOkP via IFTTT

Biologists are using comparative metabologenomics to try to uncover what may be 'silencing' Streptomyces and preventing it from producing desirable compounds encoded by its genes. from Top Health News -- ScienceDaily https://ift.tt/3j3j3YV via IFTTT

Researchers have used advanced electron microscopy (EM) technology to see how human viruses move in high resolution in a near-native environment. The visualization technique could lead to improved understanding of how vaccine candidates and treatments behave and function as they interact with target cells. from Top Health News -- ScienceDaily https://ift.tt/3lf9nxe via IFTTT

Researchers have shown how the amygdala, a brain region typically associated with fear, contributes to prepulse inhibition (PPI) by activating small inhibitory neurons in the mouse brain stem. The discovery advances understanding of the systems underlying PPI and efforts to ultimately develop medical therapies for schizophrenia and other disorders by reversing pre-attentive deficits. from Top Health News -- ScienceDaily https://ift.tt/3j4ZmQl via IFTTT

Getting more sleep, by itself, does not change work productivity or overall well-being for impoverished workers in India. Naps or better-quality sleep at night may have a bigger impact, according to a new study. from Top Health News -- ScienceDaily https://ift.tt/3j7rSks via IFTTT

University of Maryland researchers discovered a way that Mycobacterium tuberculosis (Mtb), the bacterium that causes tuberculosis, can cause a person's immune cells to lower their defenses. Specifically, they identified a gene in the bacterium that suppresses immune defenses in infected human cells, which could exacerbate the infection. The findings were published on July 29, 2021, in the journal PLOS Pathogens from Top Health News -- ScienceDaily https://ift.tt/3febQnF via IFTTT

Researchers report the identification of a new target for the PARP inhibitor drug talazoparib and show that combination treatment with talazoparib and the WEE1 inhibitor adavosertib results in enhanced anti-cancer effects. from Top Health News -- ScienceDaily https://ift.tt/3fgDUXo via IFTTT

Sleep researchers have found it's possible to determine the timing of a person's internal biological clock via a single blood draw. Ultimately, the findings could lead to a simple blood test for assessing circadian rhythm and personalized recommendations for when people should eat, sleep, exercise and take medications. from Top Health News -- ScienceDaily https://ift.tt/2VoEsTW via IFTTT

Interventions to prevent obesity in children typically don't target the first 1,000 days of life - -a critical period in which environmental and nutritional cues can increase the risk for obesity. A new study demonstrates how changing parents' health behavior and how clinicians deliver care to mothers and infants decreased excess weight gain in infants. from Top Health News -- ScienceDaily https://ift.tt/3rGY4Pv via IFTTT

Treating obese mice with the cytokine known as TSLP led to significant abdominal fat and weight loss compared to controls. The animal model findings support the possibility that increasing sebum production via the immune system could be a strategy for treating obesity in people. from Top Health News -- ScienceDaily https://ift.tt/3lffVLZ via IFTTT

Neuroscientists have connected some of the dots to reveal the brain networks that give anxiety influence over decisions. The group has published a review that synthesizes results from years of brain measurements in rats and primates and relates these findings to the human brain. from Top Health News -- ScienceDaily https://ift.tt/2V4Iu4g via IFTTT

A new study shows that people who eat a diet that includes at least half a serving per day of foods high in flavonoids like strawberries, oranges, peppers and apples may have a 20% lower risk of cognitive decline. The study looked at several types of flavonoids, and found that flavones and anthocyanins may have the most protective effect. from Top Health News -- ScienceDaily https://ift.tt/3iYd9Is via IFTTT

Researchers say they have added to evidence that the compound farnesol, found naturally in herbs, and berries and other fruits, prevents and reverses brain damage linked to Parkinson's disease in mouse studies. from Top Health News -- ScienceDaily https://ift.tt/3jbb2Bk via IFTTT

A team lights a path forward for improved treatment of conditions including addiction and epilepsy and chronic pain. In a new article, they report on a wireless transcranial optogenetic simulation device that can send light through the skull rather than physically penetrating the blood-brain barrier. from Top Health News -- ScienceDaily https://ift.tt/2V9lOjf via IFTTT

Researchers have discovered the underlying genetic cause of a rare childhood disorder that mimics inflammatory bowel disease, a finding that may help researchers uncover the roots of a host of other inflammatory and autoimmune disorders. from Top Health News -- ScienceDaily https://ift.tt/37oSbxb via IFTTT

A study has found photos of a person's living space can accurately point at personality traits and the mood of the people who live there, especially as a person gets older. Applying the findings could help lead to happier lives, including for older adults with frailty or cognitive impairment that has led them to be transferred from their homes to long-term care facilities. from Top Health News -- ScienceDaily https://ift.tt/3BUmslo via IFTTT

Children whose parents regularly smoke or vape marijuana may experience viral respiratory infections, such as the common cold, more frequently than those whose parents do not smoke, according to a new study. from Top Health News -- ScienceDaily https://ift.tt/3zOsMZD via IFTTT

Researchers have developed nanobodies that efficiently block the coronavirus SARS-CoV-2 and its new variants. from Top Health News -- ScienceDaily https://ift.tt/2V6U0vT via IFTTT

Researchers have shown 'gene drive' technology, which spreads a genetic modification blocking female reproduction, works in natural-like settings. from Top Health News -- ScienceDaily https://ift.tt/3l7IdYY via IFTTT

The interdisciplinary team's work could allow scientists to accelerate the rate of discovery and study of materials that exhibit a metal-insulator transition. from Top Health News -- ScienceDaily https://ift.tt/3faE0A6 via IFTTT

'Panic buying' might be a normal human response to uncertainty after all, new research suggests. from Top Health News -- ScienceDaily https://ift.tt/3ic8Ee3 via IFTTT

Research reveals key differences between single- and double-stranded RNA, insights that may prove useful to fields from agriculture to medicine. from Top Health News -- ScienceDaily https://ift.tt/3j55tUD via IFTTT

We remember things longer if we take breaks during learning, referred to as the spacing effect. Scientists gained deeper insight into the neuronal basis for this phenomenon in mice. With longer intervals between learning repetitions, mice reuse more of the same neurons as before -- instead of activating different ones. Possibly, this allows the neuronal connections to strengthen with each learning event, such that knowledge is stored for a longer time. from Top Health News -- ScienceDaily https://ift.tt/378hOC5 via IFTTT

Middle-ear infections are a common affliction in early life, affecting more than 80% of children in the U.S. Antibiotics are often employed as a first line of defense but sometimes fail against the pathogenic bacteria that can develop in the middle ear, just behind the eardrum. In a new study, researchers explore the use of microplasma -- a highly focused stream of chemically excited ions and molecules -- as a noninvasive method for attacking the bacterial biofilms that resist antibiotic treatment in the middle ear. from Top Health News -- ScienceDaily https://ift.tt/3BYnY5R via IFTTT

A gene associated with autism spectrum disorder (ASD) and pain hypersensitivity may actually decrease itch response, according to new research. from Top Health News -- ScienceDaily https://ift.tt/3xduORp via IFTTT

A new study provides foundational information about SARS-CoV-2's spike protein. from Top Health News -- ScienceDaily https://ift.tt/3lcoszs via IFTTT

Twenty-six subjects from a cohort of 80 tested positive for SARS-CoV-2 via nasopharyngeal swab, and all 26 tested positive using gargle lavage (mouthwash), according to new research. from Top Health News -- ScienceDaily https://ift.tt/2UWYnKa via IFTTT

How long do coronaviruses remain infectious on banknotes and coins? Is it possible to become infected through contact with cash? Researchers developed a method specifically to test how many infectious virus particles can be transferred from cash to the skin in real-life conditions. Conclusion: under realistic conditions, the risk of contracting SARS-CoV-2 from cash is very low. from Top Health News -- ScienceDaily https://ift.tt/2UTYtCh via IFTTT

When people behave badly or unethically, their loved ones may judge them less harshly than they would judge a stranger who committed the same transgressions, but that leniency may come at the cost of the judger's own sense of self-worth, according to new research. from Top Health News -- ScienceDaily https://ift.tt/3laYzjl via IFTTT

Removing a protein that is often overexpressed in a rare and aggressive subtype of leukemia can help to slow the cancer's development and significantly increase the likelihood of survival, according to a new study in mice. from Top Health News -- ScienceDaily https://ift.tt/3laU0FJ via IFTTT

A meta-analysis of nearly 200,000 men revealed 22 new genetic locations that could be susceptible to inherited testicular germ cell tumors. from Top Health News -- ScienceDaily https://ift.tt/3i9zLX5 via IFTTT

Two new studies provide insights into T cell exhaustion, which could lead to potential strategies to overcome it. from Top Health News -- ScienceDaily https://ift.tt/3f8OkbQ via IFTTT

Findings underscore the importance of early, intensive treatment. The study focused on complications of youth-onset type 2 diabetes. Overall, researchers saw a steady decline in blood glucose control over 15 years. from Top Health News -- ScienceDaily https://ift.tt/3f8rT6C via IFTTT

The blood groups of three Neanderthals one Denisovan have been determined by a team including a palaeoanthropologist, population geneticists, and haematologists. Their research provides new data for understanding the origins, history, and health of these extinct hominin lineages. from Top Health News -- ScienceDaily https://ift.tt/3f8rS2y via IFTTT

New research has identified proteins in a common weed which could play havoc for farmers growing gluten-free crops, such as millet, buckwheat and sorghum, and people suffering from gluten intolerance. from Top Health News -- ScienceDaily https://ift.tt/3icPfde via IFTTT

A protein that helps regulate calcium signaling within heart cells could play a key role in preventing chronic heart failure, according to a new study. from Top Health News -- ScienceDaily https://ift.tt/3leJ1LP via IFTTT

Emergency department visit rates because of an opioid overdose increased by 28.5 percent across the U.S. in 2020, compared to 2018 and 2019, recent research finds. from Top Health News -- ScienceDaily https://ift.tt/3zLXAKO via IFTTT

With the Olympics underway, higher testosterone has often been linked to sporting success, and other kinds of success too. But beyond sport, new research has found little evidence that testosterone meaningfully influences life chances for men or women. In fact, the study suggests that despite the social myths surrounding testosterone, it could be much less important than previously thought. from Top Health News -- ScienceDaily https://ift.tt/2UQLKAl via IFTTT

Researchers have developed a computational tool that identifies cancer driver mutations for each tumor type. from Top Health News -- ScienceDaily https://ift.tt/3ia4Aej via IFTTT

Researchers surveyed 1,175 surgeons and surgical trainees from across the U.S. to study their or their partner's pregnancy experiences. They found that 48 percent of surveyed female surgeons experienced major pregnancy complications, with those who operated 12-or-more hours per week during the last trimester of pregnancy at a higher risk compared to those who did not. from Top Health News -- ScienceDaily https://ift.tt/2V2KMRj via IFTTT

Using advanced imaging technology, scientists have provided an unprecedented understanding of the BRCA1-BARD1 protein complex, which is often mutated in patients with breast or ovarian cancer. Their paper identifies aspects of how BRCA1-BARD1 functions, supporting future translational research, cancer prevention efforts and drug development. from Top Health News -- ScienceDaily https://ift.tt/37dvXOd via IFTTT

MicroCT of infected human lung tissue, along with histology and immunohistochemistry, was used to construct images of TB granulomas, airways and vasculature. from Top Health News -- ScienceDaily https://ift.tt/3j2D1TH via IFTTT

Brain imaging and mathematical modeling reveal previously unreported mechanistic features of symptoms associated with major depressive disorder. from Top Health News -- ScienceDaily https://ift.tt/3l7rDs4 via IFTTT

In a major advancement in the field of gene therapy for rare and devastating diseases, researchers have developed a "dimmer switch" system that can control levels of proteins expressed from gene therapy vectors. The system is based on alternative RNA splicing using an orally available small molecule and works effectively in tissues throughout the body, including the brain. from Top Health News -- ScienceDaily https://ift.tt/2UQBMyT via IFTTT

In an attempt to find out why the long-term outcomes are poorer for patients with lobular breast cancer -- which affects some 40,000 women a year -- researchers began looking at the role of the protein MDC1 in tumor cells. from Top Health News -- ScienceDaily https://ift.tt/2V2xWCy via IFTTT

Researchers have shown that postpartum depression can inhibit a mother's ability to instill healthy tooth brushing habits in children. The study demonstrates the need to foster greater mental support and management for mothers and incorporate these factors when assessing children's oral health. from Top Health News -- ScienceDaily https://ift.tt/3l6jwvP via IFTTT

Women often struggle with managing their weight and other health risk factors, such as high cholesterol, once they transition through menopause. A new study suggests that dancing may effectively lower cholesterol levels, improve fitness and body composition and in the process, improve self-esteem. from Top Health News -- ScienceDaily https://ift.tt/2WviSxU via IFTTT

Although cats have lived alongside humans for millennia, it remains a dogs' world. This bias has historically bled into science as well. It's time for cats to get their day, argues veterinary medicine experts. Cats, they say, have the potential to be a valuable model organism for geneticists, as the feline genome is ordered similarly to humans. from Top Health News -- ScienceDaily https://ift.tt/3zO3P0m via IFTTT

Tragically, the opioid epidemic has led to an increase in accidental and premature deaths, which has also increased the number of hearts available for potential organ donation. Receiving a heart from a donor who used illicit drugs does not impact the recipient's survival, according to a group of researchers from Virginia, Arizona and Indiana. from Top Health News -- ScienceDaily https://ift.tt/3xl1vwB via IFTTT

Healthy lifestyle factors such as abstinence from smoking and drinking, low body mass index, and exercise correlated with decreased cancer incidence, even in individuals with a high genetic risk. from Top Health News -- ScienceDaily https://ift.tt/3l5LVCd via IFTTT

A new study of cells shows that antibodies produced by the body in response to COVID-19 may be triggering a blood clotting response in patients with severe disease. from Top Health News -- ScienceDaily https://ift.tt/374WZYb via IFTTT

Scientists have developed a mathematical simulator to guide isolation policies for patients infected with the new coronavirus. from Top Health News -- ScienceDaily https://ift.tt/3BOBSHR via IFTTT

A team has demonstrated that fermenting drinks fortified with pea and rice proteins yields the same quality of protein as casein, an animal protein found in milk. from Top Health News -- ScienceDaily https://ift.tt/3f8Mjfs via IFTTT

Swimming a few laps likely won't turn your child into the next Katie Ledecky or Michael Phelps, but it just might help them become the next J.K. Rowling or Stephen King. A recent study suggests aerobic exercise, such as swimming, can boost kids' vocabulary growth. from Top Health News -- ScienceDaily https://ift.tt/2Wwj0NF via IFTTT

A new study has found plastic accumulation in foods may be underestimated. There is also concern these microplastics will carry potentially harmful bacteria such as E. coli, which are commonly found in coastal waters, up the food chain. from Top Health News -- ScienceDaily https://ift.tt/3zFk0wY via IFTTT

New research has uncovered an essential mechanism coordinating the processes of cell division and adhesion within humans. This discovery has profound potential for advancing understanding of cell adhesion signalling in cancerous tumor progression and metastasis. from Top Health News -- ScienceDaily https://ift.tt/3BM2TM9 via IFTTT

The cost-effectiveness of drug synthesis depends on a number of factors, including the amount of waste produced. A team of researchers have now discovered a catalyst that achieves exceptionally high-precision addition of hydrogen to carbon-carbon bonds, improving targeted synthesis by avoiding convoluted multi-step processes, and reducing wasteful by-products. The authors herald the reaction as especially useful in the production of complex natural substances such as pheromones. from Top Health News -- ScienceDaily https://ift.tt/3BNaw4O via IFTTT

A research team has directly reprogrammed whale somatic cells to neuronal cells, and conducted a neurotoxicity test using these cells. Exposure to a metabolite (4?OH-CB72) of polychlorinated biphenyls, ubiquitous environmental pollutants, caused apoptosis in the reprogrammed neurons. Transcriptome analysis of 4?OH-CB72-treated whale neurons showed altered expressions of genes associated with oxidative phosphorylation, chromatin degradation, axonal transport, and neurodegenerative diseases. from Top Health News -- ScienceDaily https://ift.tt/3j3oFCy via IFTTT

Women have several choices for long-lasting, reversible contraceptives, but most options for men are either single-use, such as condoms, or difficult to reverse, like vasectomies. Now, in a step toward a safe, long-lasting and reversible male contraceptive, researchers have developed magnetic, biodegradable nanomaterials that reduced the likelihood of mice fathering pups for at least 30 days. from Top Health News -- ScienceDaily https://ift.tt/3yayWmp via IFTTT

Can you think of three words that are completely unrelated to one another? What about four, five, or even ten? According to researchers, this simple exercise of naming unrelated words and then measuring the semantic distance between them could serve as an objective measure of creativity. from Top Health News -- ScienceDaily https://ift.tt/3BKeJ9j via IFTTT

A 15-center study of 175 patients with poorly controlled type 2 diabetes found that continuous glucose monitoring, compared to blood glucose meter monitoring, or finger pricking, significantly decreased their hemoglobin A1C over eight months. from Top Health News -- ScienceDaily https://ift.tt/2WnsGdg via IFTTT

Scientists have developed a statistical framework that incorporates key COVID-19 data -- such as case counts and deaths due to COVID-19 -- to model the true prevalence of this disease in the United States and individual states. Their approach projects that in the U.S. as many as 60 percent of COVID-19 cases went undetected as of March 7, 2021, the last date for which the dataset they employed is available. from Top Health News -- ScienceDaily https://ift.tt/3kYdv4l via IFTTT

A new study reports that among individuals who had an allergic reaction to their first mRNA COVID-19 vaccine dose, all who went on to receive a second dose tolerated it. Even some who experienced anaphylaxis following the first dose tolerated the second dose. from Top Health News -- ScienceDaily https://ift.tt/3rBdZyB via IFTTT

The visual cortex stores and remembers individual images, but when they are grouped into a sequence, mice can't recognize that without guidance from the hippocampus, according to a new study. from Top Health News -- ScienceDaily https://ift.tt/3zCuv4d via IFTTT

Improving air quality may improve cognitive function and reduce dementia risk, according to several recent studies. from Top Health News -- ScienceDaily https://ift.tt/3f0q3oe via IFTTT

Even in the absence of bark beetle outbreaks and wildfire, trees in Colorado subalpine forests are dying at increasing rates from warmer and drier summer conditions, found recent research. from Top Health News -- ScienceDaily https://ift.tt/3iO3sw4 via IFTTT

In an analysis of almost 3 million patients taking a single high blood pressure medication for the first time, angiotensin receptor blockers (ARBs) were as good as angiotensin-converting enzyme (ACE) inhibitors at preventing cardiovascular events linked to hypertension, including heart attack, stroke and heart failure. 51 possible side effects and safety concerns were examined: The patients taking ARBs were found to be significantly less likely to develop tissue swelling, cough, pancreas inflammation and bleeding in the digestive tract. from Top Health News -- ScienceDaily https://ift.tt/3i54GUz via IFTTT

A new study highlights the power of comprehensive whole genome, whole exome and RNA sequencing to better understand and treat each patient's cancer. from Top Health News -- ScienceDaily https://ift.tt/3iFk2OI via IFTTT

Researchers are pushing organ-on-a-chip devices to new levels that could change the way clinicians approach cancer treatment, particularly ovarian cancer. from Top Health News -- ScienceDaily https://ift.tt/3zyRQnl via IFTTT

Researchers have developed two solutions with potential to overcome a key clinical limitation of immune cell therapies. from Top Health News -- ScienceDaily https://ift.tt/3iLj2J1 via IFTTT

There are many reasons that an intranasal vaccine against the SARS-CoV-2 virus would be helpful in the fight against COVID-19 infections, immunologists write in a new article. from Top Health News -- ScienceDaily https://ift.tt/3iJZLYc via IFTTT

Long thought of as a generic alarm system, the locus coeruleus may actually be a sophisticated regulator of learning and behavior, according to a new review. from Top Health News -- ScienceDaily https://ift.tt/3hZShkX via IFTTT

In a wealth and longevity study to incorporate siblings and twin pair data, researchers analyzed the midlife net worth of adults (mean age 46.7 years) and their mortality rates 24 years later. They discovered those with greater wealth at midlife tended to live longer. from Top Health News -- ScienceDaily https://ift.tt/3kWWkQy via IFTTT

New research by an Executive PhD Research student at the Business School (formerly Cass) outlines how elderly patients with neurological conditions are significantly more likely to develop delirium shortly after they are hospitalised, and those admitted on Sunday and Tuesday are more likely to develop the disorder. from Top Health News -- ScienceDaily https://ift.tt/3i2bSB0 via IFTTT

Researchers have discovered that spontaneous impulses of dopamine, the neurological messenger known as the brain's 'feel good' chemical, occur in the brain of mice. The study found that mice can willfully manipulate these random dopamine pulses for reward. from Top Health News -- ScienceDaily https://ift.tt/3zsi6jl via IFTTT

Millennials, often referred to as the 'job-hopping generation,' represent a group of young workers who once grabbed the national spotlight with their publicized demands for 'fun' work perks, such as happy hours. However, researchers have discovered today's young workers -- ages 21-34 -- represent a life-stage shift toward placing more value on having respectful communication in the workplace over trendy work perks. from Top Health News -- ScienceDaily https://ift.tt/3iCRrJP via IFTTT

Scientists have built an artificial intelligence (AI) model that identifies chemical compounds that promote healthy aging - paving the way towards pharmaceutical innovations that extend a person's lifespan. from Top Health News -- ScienceDaily https://ift.tt/3eL6ikr via IFTTT

Researchers shrunk a deadly glioblastoma tumor by more than a third using a helmet generating a noninvasive oscillating magnetic field that the patient wore on his head while administering the therapy in his own home. The 53-year-old patient died from an unrelated injury about a month into the treatment, but during that short time, 31% of the tumor mass disappeared. The autopsy of his brain confirmed the rapid response to the treatment. from Top Health News -- ScienceDaily https://ift.tt/3kZV9jJ via IFTTT

As a newborn mammal opens its eyes for the first time, it can already make visual sense of the world around it. But how does this happen before they have experienced sight? from Top Health News -- ScienceDaily https://ift.tt/3kMz1t0 via IFTTT

A new tool that enables thousands of tiny experiments to run simultaneously on a single polymer chip will let scientists study enzymes faster and more comprehensively than ever before. from Top Health News -- ScienceDaily https://ift.tt/3rx3eh0 via IFTTT

A new study shows that the stiffness of protein fibers in tissues, like collagen, are a key component in controlling the movement of cells. The groundbreaking discovery provides the first proof of a theory from the early 1980s and could have a major impact on fields that study cell movement from regenerative medicine to cancer research. from Top Health News -- ScienceDaily https://ift.tt/3wSVMOc via IFTTT

Researchers have developed a way to analyze how individual immune cells react to the bacteria that cause tuberculosis. It could pave the way for new vaccine strategies and provide insights into fighting other infectious diseases. from Top Health News -- ScienceDaily https://ift.tt/3hZBLS0 via IFTTT

New hydrogels mimic intestines when lined with epithelial cells. A study demonstrated hydrogels in various stiffnesses are valuable for learning the dynamics of pathogens that cause diarrhea and other intestinal diseases. from Top Health News -- ScienceDaily https://ift.tt/3y09OPq via IFTTT

An innovative testing platform that more closely mimics what cancer encounters in the body may allow for more precise, personalized therapies by enabling the rapid study of multiple therapeutic combinations against tumor cells. The platform uses a three-dimensional environment to more closely mirror a tumor microenvironment. from Top Health News -- ScienceDaily https://ift.tt/2WcbmYD via IFTTT

After examining nearly the entire human genome for genetic changes that increase risk of aneurysm, researchers discovered a new change in the genetic code of a transcription factor. from Top Health News -- ScienceDaily https://ift.tt/3xUb72h via IFTTT

Participation in elite adult rugby may be associated with changes in brain structure, according to a new study. from Top Health News -- ScienceDaily https://ift.tt/3zp7WzV via IFTTT

Reduced mobility induced by the COVID-19 restrictions had only minor influence on particulate pollution levels, according to atmosphere studies in the Po Valley region of northern Italy. Eventually computer simulations indicated that the change in air quality led to an increase in secondary aerosol formation. from Top Health News -- ScienceDaily https://ift.tt/3rFF4Rz via IFTTT

Researchers report the first structural confirmation that endogenous -- or self-made -- molecules can set off innate immunity in mammals via a pair of immune cell proteins called the TLR4-MD-2 receptor complex. The work has wide-ranging implications for finding ways to treat and possibly prevent autoimmune diseases such as multiple sclerosis and antiphospholipid syndrome. from Top Health News -- ScienceDaily https://ift.tt/36WGehI via IFTTT

New research has uncovered the early assembly of gamma-secretase, a protein complex linked to numerous cellular processes including the development of Alzheimer's disease. In a first step, two dimeric subcomplexes are formed, which independently exit the ER and only afterwards assemble into a four-subunit complex. This 'buckle up' mechanism is thought to prevent premature assembly and activity. from Top Health News -- ScienceDaily https://ift.tt/3iAMAZz via IFTTT

Over the last few decades, neurodegenerative diseases became one of the top 10 global causes of death. Researchers worldwide are making a strong effort to understand neurodegenerative diseases pathogenesis, which is essential to develop efficient treatments against these incurable diseases. A team of researchers found out the implication of lysosomes in the spread of Parkinson's disease. from Top Health News -- ScienceDaily https://ift.tt/3zrtOus via IFTTT

A new study shows that deep learning models trained on large sets of cancer genetic and tissue histology data can easily identify the institution that submitted the images. from Top Health News -- ScienceDaily https://ift.tt/3kT7QMO via IFTTT

Findings could help pave the way for cancer therapies that target TAF12, potentially stopping transcription in cancer cells and helping decrease the growth of cancerous tumors. from Top Health News -- ScienceDaily https://ift.tt/3rqGyyS via IFTTT

Researchers have found that omega-3 levels in blood erythrocytes are very good mortality risk predictors. The study used data from a long-term study group, the Framingham Offspring Cohort, which has been monitoring residents of this Massachusetts town, in the United States, since 1971 and concludes that, 'Having higher levels of these acids in the blood, as a result of regularly including oily fish in the diet, increases life expectancy by almost five years.' from Top Health News -- ScienceDaily https://ift.tt/3iESj0u via IFTTT

Some antibiotics appear to be effective against a form of skin cancer known as melanoma. Researchers examined the effect of these antibiotics on patient-derived tumors in mice. from Top Health News -- ScienceDaily https://ift.tt/3wSqdEc via IFTTT

New research represents one of the first studies to examine the effectiveness of targeted lionfish removals from both an ecological and a socio-economic perspective. from Top Health News -- ScienceDaily https://ift.tt/3ruE4ze via IFTTT

With the application of a novel three-dimensional imaging technology, researchers have discovered that one portion of the autonomic nervous system in the liver undergoes severe degeneration in non-alcoholic fatty liver disease. The study, which is conducted in mice and human liver tissue, shows that the degeneration of nerves is correlated with the severity of liver pathology. from Top Health News -- ScienceDaily https://ift.tt/3ztkPc7 via IFTTT

Researchers have developed a tougher, safer bicycle helmet using a combination of materials. The new helmet prototype has higher energy absorption, reducing the amount of energy transferred to a cyclist's head in the event of an accident and likely lowering the chances of serious injury. from Top Health News -- ScienceDaily https://ift.tt/3iCjLMn via IFTTT

Researchers have published evidence of the sustained benefits of an investigational antipsychotic treatment for people with dementia-related psychosis. from Top Health News -- ScienceDaily https://ift.tt/3izXsHf via IFTTT

Scientists have successfully reversed age-related memory loss in mice and say their discovery could lead to the development of treatments to prevent memory loss in people as they age. from Top Health News -- ScienceDaily https://ift.tt/3zuS4fr via IFTTT

Scientists have developed a 'nanobody' - a small fragment of a llama antibody - that is capable of chasing out human cytomegalovirus (HCMV) as it hides away from the immune system. This then enables immune cells to seek out and destroy this potentially deadly virus. from Top Health News -- ScienceDaily https://ift.tt/3hW3H92 via IFTTT

Researchers reported the development of a transferrable and integrative type I CRISPR-based platform that can efficiently edit the diverse clinical isolates of Pseudomonas aeruginosa, a superbug capable of infecting various tissues and organs and a major source of nosocomial infections. The technique can accelerate the identification of resistance determinants of multidrug resistant (MDR) pathogens and the development of novel anti-resistance strategies. from Top Health News -- ScienceDaily https://ift.tt/36UOajy via IFTTT

More than 820 million people in the world don't have enough to eat, while climate change and increasing competition for land and water are further raising concerns about the future balance between food demand and supply. The results of a new study can be used to benchmark global food security projections and inform policy analysis and public debate on the future of food. from Top Health News -- ScienceDaily https://ift.tt/3BuQQSZ via IFTTT

The standardized non-invasive clear cell likelihood score (ccLS) -- derived from MRI -- correlates with the growth rate of small renal masses (cT1a, <4 cm) and may help guide personalized management. from Top Health News -- ScienceDaily https://ift.tt/3eMZfrf via IFTTT

Researchers have shown how the brain communicates to blood vessels when in need of energy, and how these blood vessels respond by relaxing or constricting to direct blood flow to specific brain regions. from Top Health News -- ScienceDaily https://ift.tt/3y0moyb via IFTTT

A new model mimics physiologic loads on engineering heart muscle tissues, yielding an unprecedented view of how genetics and mechanical forces contribute to heart muscle function. from Top Health News -- ScienceDaily https://ift.tt/3wZXNrI via IFTTT

Exoskeletons - wearable devices used by workers on assembly lines or in warehouses to alleviate stress on their lower backs - may compete with valuable resources in the brain while people work, canceling out the physical benefits of wearing them, a new study suggests. from Top Health News -- ScienceDaily https://ift.tt/2W5c4GV via IFTTT

Commonly accepted advice to keep a straight back and squat while lifting in order to avoid back pain has been challenged by new research. The research examined people who had regularly performed manual lifting through their occupation for more than five years and found those who experienced low back pain as a result were more likely to use the recommended technique of squatting and keeping a straight back, while those without back pain tended not to adhere to the recommended lifting advice. from Top Health News -- ScienceDaily https://ift.tt/3hWlixK via IFTTT

Older people appear to have fewer antibodies against the novel coronavirus, a new laboratory study suggests. With vaccine uptake slowing in Oregon and across United States, researchers say their findings underscore the importance of promoting vaccinations in local communities. from Top Health News -- ScienceDaily https://ift.tt/3kMEYpB via IFTTT

During cell division, chromosomes are duplicated and separated so that one copy of each chromosome is inherited by each of the two emerging daughter cells. Correct distribution of chromosomes requires high accuracy and defects in this process can cause aberrant distribution of chromosomes and facilitate cancer development. By analyzing the structure of the protein responsible for chromosome separation, a team has shed light on the mechanisms controlling this essential player in cell division. from Top Health News -- ScienceDaily https://ift.tt/3iyJZiW via IFTTT

Researchers have developed a cell culture test to detect substances that are directly or indirectly harmful to embryos. Based on an existing test used for developing new drugs and chemicals, the augmented version is designed to help reduce the number of animal experiments. from Top Health News -- ScienceDaily https://ift.tt/3hVrrdF via IFTTT

A global multidisciplinary group of HIV experts has developed a consensus statement identifying the key issues health systems must address in order to move beyond the longtime emphasis on viral suppression to instead deliver integrated, person-centered healthcare for people living with HIV throughout their lives. from Top Health News -- ScienceDaily https://ift.tt/3kPVLbc via IFTTT

Researchers have identified an immune protein tied to the rare neurodegenerative condition known as Niemann-Pick disease type C. The finding, made in mouse models, could offer a powerful new therapeutic target for Niemann-Pick disease type C, a condition that was identified more than a century ago but still lacks effective treatments. from Top Health News -- ScienceDaily https://ift.tt/36SQLdW via IFTTT

In a new study that combines assessments of the risks of toxic emissions, nontoxic emissions and people's vulnerability to them, researchers found a strong and statistically significant relationship between the spatial distribution of global climate risk and toxic pollution. from Top Health News -- ScienceDaily https://ift.tt/3BsE8nW via IFTTT

The oral targeted therapy drug ibrutinib is an effective treatment option for high-risk hairy cell leukemia, according to a new study. from Top Health News -- ScienceDaily https://ift.tt/3BqGAeH via IFTTT

Babies who were breastfed, even for a few days, had lower blood pressure at 3 years of age than children who had never been breastfed. Toddlers who had been breastfed had lower blood pressure regardless of their body mass index or their mothers' social, health or lifestyle factors. from Top Health News -- ScienceDaily https://ift.tt/3zkjQuY via IFTTT

A new study has found that infants born within three kilometers of oil and natural gas drilling facilities in Texas had slightly lower birthweights than those born before drilling began in their vicinity. from Top Health News -- ScienceDaily https://ift.tt/3iCP3Ti via IFTTT

Regulatory T cells (Tregs) help control inflammation and autoimmunity in the body. Unfortunately, it has proven difficult to find the right molecular ingredients to induce stable iTregs. Now a new study reports that Vitamin C and TET proteins can work together to give Tregs their life-saving power. from Top Health News -- ScienceDaily https://ift.tt/3zhuKkY via IFTTT

The parasites that cause severe malaria are well-known for the sinister ways they infect humans, but new research may lead to drugs that could block one of their most reliable weapons: interference with the immune response. from Top Health News -- ScienceDaily https://ift.tt/3iyoHSD via IFTTT

Scientists have shown that frailty contributes to neurocognitive decline in young adult survivors of childhood cancer. from Top Health News -- ScienceDaily https://ift.tt/3eHVfZa via IFTTT

An international team of researchers is combining soft scalp electronics and virtual reality in a brain-interface system. from Top Health News -- ScienceDaily https://ift.tt/3eFBqSa via IFTTT